StackTerminal.Health

Glycine

Inhibitory neurotransmitter and structural amino acid; 3 g before bed shows evidence for improving sleep quality and reducing daytime fatigue.

sleeprecoveryconnective-tissue
Dosing model
FLATFixed dose (no body-weight scaling).
Min dose
3000 mg
Max dose
3000 mg
Rounding
500 mg

Stacks containing Glycine

Public community stacks that include this ingredient.

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sleepwomens-health

Cycle-phase support focused on calm and sleep quality without stimulants.

Vitex agnus-castus
20mg
Glycine
3000mg
L-Theanine
200mg
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sleep

Improves sleep quality without heavy sedation or melatonin.

Glycine
3000mg
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recoverysleep

Designed to support sleep quality, parasympathetic activation, and overnight recovery without heavy sedation.

Magnesium Glycinate
400mg
Glycine
3000mg
L-Theanine
200mg
+ 1 more supplements
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sleep

Supports parasympathetic activation before sleep.

Apigenin
50mg
Glycine
3000mg
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recoverysleepfocus

Supports training consistency under physical and mental stress.

Ashwagandha
600mg
Glycine
3000mg
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recoverysleep

Supports sleep onset with minimal next-day grogginess.

Melatonin
3mg
Glycine
3000mg
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Evidence
2 records
Daytime sleepiness and performance after sleep restriction
Healthy adults with partial sleep restrictionRCT (double-blind, placebo-controlled, crossover)
Moderate

3 g glycine before bed significantly reduced daytime sleepiness, fatigue, and cognitive impairment following 25% sleep restriction; mechanism involves core body temperature reduction via SCN NMDA receptors.

Dose: 3000 mg Duration: 3 nights
Well-tolerated at 3 g; higher doses not well-characterized for sleep specifically.
Collagen synthesis / connective tissue support
Recreationally active malesRCT (mechanistic)
Moderate

15 g gelatin (rich in glycine and proline, with vitamin C) before intermittent exercise doubled collagen synthesis markers (P1NP) vs. placebo; glycine is the most abundant amino acid in collagen (~33%).

Dose: 15000 mg Duration: Acute (pre-exercise)
Study used gelatin + vitamin C, not isolated glycine; glycine is rate-limiting for collagen synthesis.
Forms
Glycine powder or capsules
3 g taken before sleep; sweet taste makes powder palatable.