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Cardiovascular Health and Blood Pressure Support

B84· Mostly solid
Public 20 Apr 2026

Combining Red Yeast Rice with Garlic can support cardiovascular health and improve blood pressure. Red Yeast Rice is known for its cholesterol-lowering effects, while Garlic supports cardiovascular health by improving blood pressure and reducing inflammation.

Cardiovascular Health and Blood Pressure Support
Red Yeast Rice
Daily with meals
MODERATE
600mg
Garlic (Allium sativum)
Daily with meals
MODERATE
1200mg
No interactions detected
Each dose includes evidence rationale · doses personalized to your weight
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Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Garlic (Allium sativum)
Take ~1h before the intended effect window
Reaches peak plasma concentration in ~1h. Half-life ~2h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements
2 items
Daily with meals
Red Yeast Rice is known for its cholesterol-lowering effects.
600mg
LDL cholesterol reduction
High
Population: Adults with hypercholesterolemia
Study type: Systematic review and Meta-analysis
Dose context: 1200 mg typical • Duration: 4-24 weeks

Red Yeast Rice extract significantly reduced total cholesterol and LDL cholesterol levels.

Citation: Trogkanis et al. (2024). Safety and Efficacy of the Consumption of the Nutraceutical 'Red Yeast Rice Extract' for the Reduction of Hypercholesterolemia in Humans: A Systematic Review and Meta-Analysis. Nutrients.DOI: 10.3390/nu16101453
Lipid profile improvement
High
Population: Adults with dyslipidemia
Study type: Systematic review and Meta-analysis
Dose context: 1200 mg typical

RYR supplementation significantly lowered total cholesterol, LDL-C, and triglycerides, and increased HDL-C.

Citation: Osadnik et al. (2022). A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults. Cochrane Database of Systematic Reviews.DOI: 10.1016/j.phrs.2022.106402
LDL cholesterol reduction
Moderate
Population: Japanese adults with mild dyslipidemia
Study type: Randomized trial
Dose context: 1200 mg typical

Low dose RYR with monacolin K lowered LDL cholesterol and blood pressure.

Citation: Minamizuka et al. (2021). Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial. International Journal of Molecular Sciences.DOI: 10.3390/nu15122682
Daily with meals
Garlic supports cardiovascular health by improving blood pressure.
1200mg
blood pressure reduction
Moderate
Population: individuals with hypertension
Study type: Systematic review
Dose context: 1200 mg typical

Garlic can reduce blood pressure, waist circumference, body mass index, LDL-c, non-HDL-c, total cholesterol, triglycerides, and inflammatory markers.

Citation: Imaizumi et al. (2023). Garlic: A systematic review of the effects on cardiovascular diseases. Critical Reviews in Food Science and Nutrition.DOI: 10.1080/10408398.2022.2043821
antimicrobial effects
Low
Population: general population
Study type: Systematic review
Dose context: 1200 mg typical

Garlic has been used as an alternative treatment for vulvovaginal candidiasis.

Citation: Martin Lopez et al. (2015). Candidiasis (vulvovaginal). Critical Reviews in Food Science and Nutrition.DOI: 10.1080/10408398.2021.2024131
lipid profile improvement
Low
Population: adults with hypercholesterolemia
Study type: Systematic review
Dose context: 1200 mg typical

Garlic supplements did not demonstrate a significant decrease in LDL-C compared with placebo.

Citation: Osadnik et al. (2022). A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults. Archives of Endocrinology and Metabolism.DOI: 10.1016/j.phrs.2022.106402

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