Cardiovascular Health and Longevity

B84· Mostly solid

Public • 20 Apr 2026

Combining Astaxanthin with Olive Leaf Extract can support cardiovascular health and longevity. Astaxanthin is a potent antioxidant that reduces oxidative stress, while Olive Leaf Extract supports cardiovascular health by improving blood pressure and reducing inflammation.

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Cardiovascular Health and Longevity

cardiovascular longevity antioxidant

Astaxanthin

Daily with meals

MODERATE

8mg

Olive Leaf Extract (Oleuropein)

Daily with meals

MODERATE

500mg

No interactions detected

Each dose includes evidence rationale · doses personalized to your weight

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Interaction Analysis

Pharmacokinetic + pair-level checks

Timing optimizations

Astaxanthin

Take ~8h before the intended effect window

Reaches peak plasma concentration in ~8h. Half-life ~16h.

Olive Leaf Extract (Oleuropein)

Take ~1h before the intended effect window

Reaches peak plasma concentration in ~1h. Half-life ~2h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements

2 items

AstaxanthinModerate

Daily with meals •

Astaxanthin is a potent antioxidant that reduces oxidative stress.

Buy ingredient →

8mg

Oxidative stress markers

Moderate

Population: Firefighters

Study type: RCT

Dose context: 12 mg typical (range: 12–12 mg) • Duration: 4 weeks

Astaxanthin reduced oxidative stress markers and improved exercise capacity.

Citation: Gonzalez et al. (2024). Impact of astaxanthin supplementation on markers of cardiometabolic health and tactical performance among firefighters.•DOI: 10.1017/S0007114510005398

Study focused on occupational-related performance.

Skin elasticity and moisture

Moderate

Population: Adults with skin aging concerns

Study type: Systematic review

Dose context: 12 mg typical

Astaxanthin supplementation significantly improved skin moisture and elasticity.

Citation: Ng et al. (2021). Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies.•DOI: 10.1080/10408690590957188

Photoprotection

Moderate

Population: Healthy adults

Study type: RCT

Dose context: 12 mg typical

Astaxanthin showed photoprotective effects against UV-induced skin damage.

Citation: Ito et al. (2018). The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People-A Randomized, Double-Blind, Placebo-Controlled Trial.•DOI: 10.3390/nu10070817

Olive Leaf Extract (Oleuropein)High

Daily with meals •

Olive Leaf Extract supports cardiovascular health by improving blood pressure.

Buy ingredient →

500mg

Glucose metabolism and inflammatory markers

High

Population: Adults

Study type: Meta-analysis

Dose context: 500 mg typical

OLE and oleuropein improve glucose metabolism and reduce inflammatory markers.

Citation: Câmara Rocha Menezes et al. (2026). Metabolic and inflammatory effects of oleuropein and olive leaf extract: a systematic review and meta-analysis.•DOI: 10.1039/d5fo04235f

Postmenopausal symptom improvement

Moderate

Population: Postmenopausal women

Study type: RCT

Dose context: 250 mg typical (range: 250–250 mg) • Duration: 12 weeks

Significant improvement in menopause-specific quality of life scores.

Citation: Imperatrice et al. (2024). Olive Leaf Extract Supplementation Improves Postmenopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Parallel Study on Postmenopausal Women. Nutrients.•DOI: 10.3390/nu16223879

Blood pressure control

Moderate

Population: Hypertensive patients

Study type: RCT

Dose context: 500 mg typical

Effective in controlling blood pressure in hypertensive patients.

Citation: Lamti et al. (2025). Efficacy of olive leaf extracts in controlling blood pressure in hypertensive patients: a double-blind randomized clinical trial.•DOI: 10.1186/s12905-024-03243-4

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