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Cardiovascular Health & Longevity

Public 06 Apr 2026

Lycopene & resveratrol are combined to support cardiovascular health & longevity. Lycopene provides antioxidant support & promotes heart health, while resveratrol offers anti-aging benefits.

Cardiovascular Health & Longevity
Lycopene
Daily with meals
MODERATE
10mg
Resveratrol
Daily with meals
MODERATE
100mg
No interactions detected
Each dose includes evidence rationale · doses personalized to your weight
AI risk assessment
Context: No wearable data
PROAI risk assessment is available with Pro.
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Stack pre-check
No personal data connected — connect wearables or upload bloodwork for a personalised check
Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Lycopene
Take ~24h before the intended effect window
Reaches peak plasma concentration in ~24h. Half-life ~48h.
Resveratrol
Take ~1h before the intended effect window
Reaches peak plasma concentration in ~1h. Half-life ~3h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements
2 items
LycopeneModerate
Daily with meals
Provides antioxidant support & promotes heart health.
10mg
Prostate cancer prevention
Moderate
Population: Men with increased prostate cancer risk
Study type: Systematic review
Dose context: 15 mg typical

Lycopene supplementation was associated with a reduction in prostate cancer risk.

Citation: Sharifi-Zahabi et al. (2022). The effect of lycopene supplement from different sources on prostate specific antigen (PSA): A systematic review and meta-analysis of randomized controlled trials. Pharmacological Research.DOI: 10.1016/j.phrs.2007.01.012
Cardiovascular disease prevention
Moderate
Population: General population
Study type: Umbrella review
Dose context: 15 mg typical

Dietary lycopene intake was inversely associated with cardiovascular disease.

Citation: Li et al. (2021). Tomato and lycopene and multiple health outcomes: Umbrella review. Food Chemistry.DOI: 10.1016/j.foodchem.2020.128396
Skin photoprotection
Moderate
Population: Healthy subjects
Study type: Systematic review and meta-analysis
Dose context: 15 mg typical

Lycopene supplementation was associated with significant reductions in markers of skin photoaging.

Citation: Zhang et al. (2024). The effect of tomato and lycopene on clinical characteristics and molecular markers of UV-induced skin deterioration: A systematic review and meta-analysis of intervention trials.DOI: 10.3109/13697137.2012.742504
Daily with meals
Offers anti-aging benefits & supports cardiovascular health.
100mg
Trade-offs & context
Interaction

Inhibits CYP3A4 — clinically significant interactions with statins, blood thinners, and immunosuppressants

Tolerance

Very low oral bioavailability without formulation support (phospholipid complex, micronisation) — plain powder largely wasted

Hormones

Possible weak estrogenic activity at high doses

Metabolic health / cardiovascular markers
Low
Population: Adults with metabolic risk factors
Study type: RCTs (mixed results)
Dose context: 500 mg typical (range: 100–1000 mg) • Duration: 4–12 weeks

Inconsistent across trials; some studies show blood pressure & glucose improvements; others null.

Citation: Hausenblas et al. 2012 (meta); Liu et al. 2014 (meta)DOI: 10.1016/j.cpr.2012.10.011
Bioavailability is a key limitation; may interact with anticoagulants.
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