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Athletic Performance and Endurance

Combining Betaine Anhydrous with Cordyceps can enhance athletic performance and endurance. Betaine supports strength and power output, while Cordyceps improves oxygen utilization and endurance.

What this is for

General support

performance, endurance, recovery

Why you are seeing this

Goal fit: performance, endurance, recovery.

What to do next

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Public•Built 20 Apr 2026•2 ingredients•No interactions detected

Core stack

The main ingredients doing the work.

2 key items

Betaine AnhydrousModerate

30 min pre-workout •

Betaine supports strength and power output.

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2500mg

serum betaine concentration

Moderate

Population: resistance-trained men

Study type: RCT

Dose context: 6000 mg typical (range: 6000–6000 mg) • Duration: 14 days

The study determined that a 28-day washout period was sufficient to return serum betaine concentrations to baseline after supplementation.

Citation: Machek et al. (2022). Human Serum Betaine and Associated Biomarker Concentrations Following a 14 Day Supplemental Betaine Loading Protocol and during a 28 Day Washout Period: A Pilot Investigation. Nutrients.•DOI: 10.3390/nu14030498

muscular endurance

Moderate

Population: recreationally trained males

Study type: RCT

Dose context: 6000 mg typical (range: 6000–6000 mg) • Duration: 14 days

Betaine supplementation combined with blood flow restriction training improved one-leg press performance & affected exercise-associated biomarkers.

Citation: Machek et al. (2022). The Impacts of Combined Blood Flow Restriction Training and Betaine Supplementation on One-Leg Press Muscular Endurance, Exercise-Associated Lactate Concentrations, Serum Metabolic Biomarkers, and Hypoxia-Inducible Factor-1α Gene Expression. European Journal of Applied Physiology.•DOI: 10.3390/nu14235040

liver biochemistries & histological markers

Low

Population: patients with nonalcoholic steatohepatitis

Study type: Pilot study

Dose context: 2500 mg typical

Betaine was shown to raise S-adenosylmethionine levels, potentially decreasing hepatic steatosis in patients with nonalcoholic steatohepatitis.

Citation: Abdelmalek et al. (2001). Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Journal of Clinical Medicine.•DOI: 10.1016/s0002-9270(01)02691-0

Cordyceps (Ophiocordyceps sinensis / militaris)Low

30 min pre-workout •

Cordyceps improves oxygen utilization and endurance.

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1000mg

Aerobic exercise capacity & VO2max

Low

Population: Healthy young adults

Study type: RCT

Dose context: 2000 mg typical (range: 1000–4000 mg) • Duration: 3 weeks

A 3-week RCT of a Cordyceps militaris-containing mushroom blend found VO2max significantly improved (+4.8 ml/kg/min; p=0.042) & time to exhaustion increased (+69.8 s) compared to placebo; acute supplementation (1 week) showed no effect, suggesting chronic dosing is required.

Citation: Hirsch KR, Smith-Ryan AE, Roelofs EJ, Trexler ET, Mock MG. Cordyceps militaris Improves Tolerance to High-Intensity Exercise After Acute and Chronic Supplementation. J Diet Suppl. 2017;14(1):42-53.•DOI: 10.1080/19390211.2016.1203386•https://pubmed.ncbi.nlm.nih.gov/27408987/

Metabolic threshold & ventilatory threshold during exercise

Low

Population: Healthy older adults (ages 50–75)

Study type: double-blind placebo-controlled RCT

Dose context: 1000 mg typical (range: 999–999 mg) • Duration: 12 weeks

A 12-week RCT of Cs-4 (Cordyceps sinensis) at 999 mg/day in 20 healthy older adults improved metabolic threshold by 10.5% (p<0.02) & ventilatory threshold by 8.5% (p=0.031) versus placebo; VO2max did not change significantly.

Citation: Chen S, Li Z, Krochmal R, Abrazado M, Kim W, Cooper CB. Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial. J Altern Complement Med. 2010;16(5):585-90.•DOI: 10.1089/acm.2009.0226•https://pubmed.ncbi.nlm.nih.gov/20804368/

Stack pre-check

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Clean

Supplements

Training load

Unknown

No flags

No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis

Pharmacokinetic + pair-level checks

No interactions detected

No known absorption conflicts, pharmacokinetic conflicts, or synergies found between the ingredients in this stack.

Decision brief

Best fit when

You are mainly trying to improve performance, endurance, recovery and want a stack that reflects those priorities.

Main watchout

No major conflict stands out more than the rest of the stack.

Strongest positive

The stack reads as coherent overall rather than a random pile of ingredients.

Athletic Performance and Endurance

performance endurance recovery

Betaine Anhydrous

30 min pre-workout

MODERATE

2500mg

Cordyceps (Ophiocordyceps sinensis / militaris)

30 min pre-workout

MODERATE

1000mg

No interactions detected

Each dose includes evidence rationale · doses personalized to your weight

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