StackTerminal.Health

Research-only: Recovery + Skin (GLOW-style grouping)

Public 2/6/2026

Adds a copper peptide often discussed in cosmetic/skin contexts to a recovery/joint pairing. Evidence is indirect and component-based.

Practical pre-check
Deterministic heuristics (stimulants, duplicates, hydration). Not medical advice.
Supplements
3
Items in this stack
Training load
Unknown load
Need more wearable data
Stimulant estimate
0 mg
Only counts explicit caffeine items
Looks clean
No obvious duplication/stimulant/hydration flags from the heuristic pass.
AI risk assessment
Context: No wearable data
No assessment yet.
Supplements
3 items
PLACEHOLDER • Lyophilized • Click to expand
Preclinical repair signals; limited human evidence.
1mg
Safety / pharmacokinetics
Low
Population: Healthy volunteers
Study type: Registered phase 1 trial (results not posted)
Dose context: • Duration: See registry

A phase 1 safety/PK study in healthy volunteers was registered; results were not posted and the submission was canceled per later reviews, limiting interpretability.

Citation: ClinicalTrials.gov NCT02637284 — PCO-02 Safety and Pharmacokinetics Trialhttps://clinicaltrials.gov/study/NCT02637284
Soft tissue healing signals (preclinical)
Low
Population: Animal models (multiple tissues)
Study type: Review (preclinical-focused)
Dose context:

Multiple preclinical models report improvements in healing-related endpoints; translation to humans remains unproven.

Citation: Cushman et al., Local and Systemic Peptide Therapies for Soft Tissue Healing (2024)https://pmc.ncbi.nlm.nih.gov/articles/PMC11426299/
Musculoskeletal healing (preclinical)
Low
Population: Animal injury models (multiple tissues)
Study type: Narrative review of preclinical evidence
Dose context:

Across animal models, BPC-157 is frequently reported to improve healing-related outcomes (tendon/ligament/muscle/bone and GI injury models), but translation to humans remains unproven.

Citation: Vasireddi et al., (2025) — Emerging Use of BPC-157 in Orthopaedic Sports Medicine (review)https://pmc.ncbi.nlm.nih.gov/articles/PMC12313605/
PLACEHOLDER • Lyophilized • Click to expand
Preclinical wound-healing biology; athlete outcomes uncertain.
1mg
Wound healing (clinical development)
Low
Population: Patients with venous stasis ulcers
Study type: Registered phase 2 trial (TB4 gel)
Dose context: • Duration: Up to 84 days (per registry)

TB4 gel has been studied in venous stasis ulcer indications; registry evidence supports clinical testing, though effect sizes depend on the specific trial and endpoint reporting.

Citation: ClinicalTrials.gov NCT00832091 — Thymosin Beta 4 in Venous Stasis Ulcershttps://clinicaltrials.gov/study/NCT00832091
Wound healing
Low
Population: Rat full-thickness wound model
Study type: Preclinical animal study
Dose context:

TB4 accelerated wound healing endpoints in a rat model compared with controls.

Citation: Malinda et al., J Invest Dermatol (1999)DOI: 10.1046/j.1523-1747.1999.00708.xhttps://pubmed.ncbi.nlm.nih.gov/10469335/
Wound healing (reviewed clinical context)
Low
Population: Stasis and pressure ulcer clinical programs
Study type: Review article
Dose context:

A review summarizes phase 2 wound-healing programs reporting faster healing in those that did heal; note that these are not sports injury RCTs.

Citation: Treadwell et al., Ann N Y Acad Sci (2012) — The regenerative peptide thymosin β4 accelerates the rate of dermal healinghttps://pubmed.ncbi.nlm.nih.gov/23050815/
GHK-CuModerate
PLACEHOLDER • Other • Click to expand
Mixed cosmetic/derm evidence; formulation-dependent.
1mg
Skin appearance / remodeling (summary of clinical + mechanistic evidence)
Moderate
Population: Humans (cosmetic/dermatologic contexts) + preclinical
Study type: Review
Dose context:

Review summarizes reported improvements in some skin measures and broad tissue-remodeling biology; quality and comparators vary widely. The authors note a surprising absence of rigorous modern clinical trials for GHK-Cu in anti-wrinkle applications despite widespread cosmetic use.

Citation: Pickart et al., Molecules (2018) — Regenerative and Protective Actions of the GHK-Cu PeptideDOI: 10.3390/molecules23081985https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/
Wrinkle improvement (objective measures)
Low
Population: Adults using topical copper tripeptide complex
Study type: Clinical study (objective evaluation)
Dose context:

One objective evaluation reported no significant improvement in wrinkles/overall skin quality, though patient satisfaction differed; underscores mixed results across formulations and endpoints.

Citation: Miller et al., Arch Facial Plast Surg (2006) — Topical copper tripeptide complex evaluationDOI: 10.1001/archfaci.8.4.252https://www.liebertpub.com/abs/doi/10.1001/archfaci.8.4.252

Discussion

No comments yet. Be the first to add context or ask a question.
Max 500 characters

Similar community stacks

Avoid reinventing the wheel: fork a community stack that matches your category tags, then edit it.

Browse all community stacks →
recoveryjointsresearch-only

Groups the two most commonly paired research peptides discussed in injury-repair circles; evidence is largely preclinical and not athlete-RCT grade.

BPC-157
1mg
TB500 (TB4 / Thymosin Beta-4)
1mg
New
View
gutdigestionresearch-only

Groups gut-inflammation oriented peptides (mostly studied in preclinical colitis/inflammation models).

KPV
1mg
BPC-157
1mg
Magnesium (Glycinate)
400mg
New
View
sleepcalmfocus

Non-stimulant cognitive/calm pairing commonly discussed in nootropic communities.

Selank
1mg
New
View
endurancefatiguereadiness

Mitochondria-oriented peptide grouping. SS-31 has clinical trials in specific mitochondrial diseases; MOTS-C is mostly preclinical.

SS-31 (Elamipretide)
1mg
MOTS-C
1mg
New
View
metabolicweight-lossclinical-only

Investigational/clinical agents with strong RCT evidence in obesity-related indications (not supplements).

Retatrutide (LY-343794)
1mg
Cagrilintide
1mg
Magnesium (Glycinate)
400mg
New
View
metabolicweight-lossclinical-only

Investigational/clinical agents with strong RCT evidence in obesity-related indications (not supplements).

Retatrutide (LY-343794)
1mg
Cagrilintide
1mg
New
View