StackTerminal.Health

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Longevity & Heart Health Base

Targets cardiometabolic markers associated with long-term health.

What this is for
General support
longevity, cardiovascular, healthspan
Why you are seeing this
Goal fit: longevity, cardiovascular, healthspan.
What to do next
Add body metrics if you want dose previews to reflect your weight rather than the reference dose.
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Buy stack
Public•Built 04 Feb 2026•2 ingredients•No interactions detected
Core stack
The main ingredients doing the work.
2 key items
Omega-3 (EPA/DHA)High
Daily •
Buy ingredient →
2000mg
Trade-offs & context
Tolerance

Fishy aftertaste/burps — take with food or use enteric-coated softgels

Interaction

Mild anticoagulant effect — caution pre-surgery or with blood thinners

Context: doses >3g EPA+DHA/day

Triglyceride reduction
High
Population: Adults with hypertriglyceridemia
Study type: Systematic review and meta-analysis of RCTs
Dose context: — (range: 2000–4000 mg)

High-dose omega-3 (≥2 g EPA+DHA/day) consistently reduces fasting triglycerides by 15–30% in adults with elevated baseline levels.

Citation: See PubMed triglyceride meta-analysis.•https://pubmed.ncbi.nlm.nih.gov/34139241/
Delayed-onset muscle soreness (DOMS) after eccentric exercise
Low
Population: Healthy adults performing eccentric exercise
Study type: Systematic review and meta-analysis of RCTs
Dose context: —

Omega-3 PUFA supplementation produced a statistically significant reduction in DOMS (MD −0.93, 95% CI −1.44 to −0.42; p=0.0004) across 12 RCTs, though the effect size fell below the minimal clinically important difference of 1.4 on a 10-point VAS. Low-quality evidence overall.

Citation: Lv ZT, Zhang JM, Zhu WT. Omega-3 Polyunsaturated Fatty Acid Supplementation for Reducing Muscle Soreness after Eccentric Exercise: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Biomed Res Int. 2020;2020:8062017.•DOI: 10.1155/2020/8062017•https://pubmed.ncbi.nlm.nih.gov/32382573/
Statistical significance without clear clinical significance; larger doses (≥6 g/day) & longer supplementation (≥7 weeks) may be required.
Cardiovascular outcomes & mortality
Moderate
Population: General adults and cardiovascular risk populations
Study type: Systematic review and meta-analysis
Dose context: —

Omega-3 supplementation associated with reductions in cardiovascular events; benefit most consistent at higher EPA+DHA doses (≥2 g/day) & in high-risk populations.

Citation: See Omega-3 cardiovascular outcome trials meta-analysis.•https://pmc.ncbi.nlm.nih.gov/articles/PMC12129820/
PMC full-text review; curated cardiovascular evidence.
Coenzyme Q10Moderate
Daily •
Buy ingredient →
200mg
Morbidity & mortality in chronic heart failure
Moderate
Population: Adults with moderate-to-severe chronic heart failure
Study type: Randomized double-blind placebo-controlled trial (Q-SYMBIO)
Dose context: 300 mg typical • Duration: 2 years

CoQ10 100 mg three times daily over 2 years reduced major adverse cardiovascular events (15% vs 26% placebo) & all-cause mortality (10% vs 18% placebo; RR 0.58, 95% CI 0.35–0.95) in addition to standard therapy.

Citation: Mortensen SA, Rosenfeldt F, Kumar A, et al. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial. JACC Heart Fail. 2014;2(6):641-9.•DOI: 10.1016/j.jchf.2014.06.008•https://pubmed.ncbi.nlm.nih.gov/25282031/
Landmark RCT; conducted in patients on background heart failure therapy.
Statin-associated muscle symptoms (myalgia, weakness, cramps)
Low
Population: Adults experiencing statin-induced myopathy
Study type: Systematic review and meta-analysis of RCTs
Dose context: —

CoQ10 supplementation significantly improved statin-associated muscle pain (WMD −1.60), weakness (WMD −2.28), cramps (WMD −1.78), & tiredness (WMD −1.75) across 12 RCTs (n=575), though plasma creatine kinase was not significantly reduced.

Citation: Qu H, Guo M, Chai H, et al. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials. J Am Heart Assoc. 2018;7(19):e009835.•DOI: 10.1161/JAHA.118.009835•https://pubmed.ncbi.nlm.nih.gov/30371340/
Symptom improvement without biochemical marker change; overall evidence quality is low due to small trial sizes.
Stack pre-check
No personal data connected — connect wearables or upload bloodwork for a personalised check
Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Omega-3 (EPA/DHA)
With fat-containing meal
Fat-soluble. Bioavailability is significantly higher when taken with food vs fasting. (Onset: ~4h, half-life: ~72h)
Coenzyme Q10
With fat-containing meal
Fat-soluble. Ubiquinol form has 3× better bioavailability than ubiquinone; fat co-ingestion further improves absorption. (Onset: ~6h, half-life: ~33h)

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

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