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Cardiovascular Health and Antioxidant Support

Combining Krill Oil with Vitamin E can support cardiovascular health and provide antioxidant protection. Krill Oil is known for its omega-3 fatty acids, supporting heart health, while Vitamin E provides antioxidant support and reduces oxidative stress.

What this is for
General support
cardiovascular, antioxidant, longevity
Why you are seeing this
Goal fit: cardiovascular, antioxidant, longevity.
What to do next
Add body metrics if you want dose previews to reflect your weight rather than the reference dose.
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Public•Built 20 Apr 2026•2 ingredients•No interactions detected
Core stack
The main ingredients doing the work.
2 key items
Krill OilModerate
Daily with meals •
Krill Oil is known for its omega-3 fatty acids, supporting heart health.
Buy ingredient →
1000mg
Knee pain reduction
Moderate
Population: Adults with knee osteoarthritis
Study type: RCT
Dose context: 2000 mg typical (range: 2000–2000 mg) • Duration: 24 weeks

Krill oil did not significantly improve knee pain compared to placebo.

Citation: Zhang et al. (2025). Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.•DOI: 10.1007/s40674-016-0041-z
Triglyceride levels
Moderate
Population: Patients with severe hypertriglyceridemia
Study type: RCT
Dose context: 1000 mg typical

Krill oil supplementation showed potential in reducing triglyceride levels.

Citation: Hill et al. (2023). A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis.•DOI: 10.3390/nu15173769
Omega-3 index
Moderate
Population: Well-conditioned power training athletes
Study type: RCT
Dose context: 1000 mg typical

Krill oil increased the HS-Omega-3 Index and plasma choline levels.

Citation: Drobnic et al. (2021). Krill-Oil-Dependent Increases in HS-Omega-3 Index, Plasma Choline and Antioxidant Capacity in Well-Conditioned Power Training Athletes.•DOI: 10.3390/nu13124237
Vitamin E (Tocopherols)Moderate
Daily with meals •
Vitamin E provides antioxidant support and reduces oxidative stress.
Buy ingredient →
50mg
cardiovascular health
Moderate
Population: general population
Study type: Meta-analysis
Dose context: 268 mg typical

Vitamin E supplementation is considered to provide health benefits against cardiovascular disease through its antioxidant activity, though results from large prospective studies are mixed.

Citation: Virk-Baker et al. (2014). Dietary acrylamide and human cancer: a systematic review of literature. BMJ.•DOI: 10.1136/bmj.j4008
age-related cognitive decline
Moderate
Population: elderly
Study type: Meta-analysis
Dose context: 268 mg typical

Peripheral tocopherol levels are associated with age-related cognitive decline and Alzheimer's disease, suggesting a potential protective role.

Citation: Ashley et al. (2021). A meta-analysis of peripheral tocopherol levels in age-related cognitive decline and Alzheimer's disease. Ophthalmology.•DOI: 10.1080/1028415x.2019.1681066
lung cancer incidence
Moderate
Population: male smokers
Study type: RCT
Dose context: 50 mg typical (range: 50–50 mg) • Duration: 5-8 years

No reduction in lung cancer incidence was observed with alpha-tocopherol supplementation; beta carotene supplementation unexpectedly increased lung cancer incidence.

Citation: Clarke et al. (2008). Vitamin E in human health and disease. Pharmacology & Therapeutics.•DOI: 10.1016/j.pharmthera.2015.12.003
Stack pre-check
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Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Krill Oil
Take ~6h before the intended effect window
Reaches peak plasma concentration in ~6h. Half-life ~5h.
Vitamin E (Tocopherols)
Take ~12h before the intended effect window
Reaches peak plasma concentration in ~12h. Half-life ~48h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

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