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Immune Support and Antioxidant Defense

B84· Mostly solid
Public • 20 Apr 2026

Combining Sea Buckthorn with Vitamin C can enhance immune function and provide antioxidant defense. Sea Buckthorn is known for its immune-boosting and antioxidant properties, while Vitamin C supports immune health and reduces oxidative stress.

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Immune Support and Antioxidant Defense
immuneantioxidantlongevity
Sea Buckthorn
Daily with meals
MODERATE
2000mg
Vitamin C
Daily with meals
MODERATE
500mg
No interactions detected
Each dose includes evidence rationale · doses personalized to your weight
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Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Vitamin C (Ascorbic Acid)
Take ~2h before the intended effect window
Reaches peak plasma concentration in ~2h. Half-life ~2h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements
2 items
Sea BuckthornModerate
Daily with meals •
Sea Buckthorn is known for its immune-boosting and antioxidant properties.
Buy ingredient →
2000mg
wound healing
Moderate
Population: patients with second-degree burns
Study type: RCT
Dose context: 2000 mg typical

Sea buckthorn was compared to silver sulfadiazine dressing & showed effectiveness in wound healing.

Citation: Abdullahzadeh et al. (2021). To compare the effect of sea buckthorn and silver sulfadiazine dressing on period of wound healing in patients with second-degree burns: A randomized triple-blind clinical trial. Journal.•DOI: 10.1111/wrr.12916
stem cell mobilization
Moderate
Population: healthy human subjects
Study type: RCT
Dose context: 2000 mg typical

Consumption of a polyphenol-rich extract from sea buckthorn berries led to rapid & selective mobilization of specific stem cell types.

Citation: Drapeau et al. (2019). Rapid and selective mobilization of specific stem cell types after consumption of a polyphenol-rich extract from sea buckthorn berries in healthy human subjects. Journal.•DOI: 10.2147/cia.s186893
vaginal atrophy improvement
Moderate
Population: postmenopausal women
Study type: RCT
Dose context: 2000 mg typical

Sea buckthorn oil intake showed positive effects on vaginal atrophy symptoms.

Citation: Larmo et al. (2014). Effects of sea buckthorn oil intake on vaginal atrophy in postmenopausal women: a randomized, double-blind, placebo-controlled study. Journal.•DOI: 10.1016/j.maturitas.2014.07.010
Vitamin CLow
Daily with meals •
Vitamin C supports immune health and reduces oxidative stress.
Buy ingredient →
500mg
Trade-offs & context
Note

Gastrointestinal Tolerance

Context: High doses of Vitamin C can cause gastrointestinal discomfort, including diarrhea.

Note

Kidney Stones

Context: Excessive intake of Vitamin C may increase the risk of kidney stones in susceptible individuals.

Cancer adjuvant (high-dose IV)
Low
Population: Patients undergoing stem cell transplantation
Study type: Randomized Controlled Trial
Dose context: 50000 mg typical • Duration: 100 days

High-dose intravenous Vitamin C improved plasma levels and showed trends toward reduced complications in stem cell transplant patients.

Citation: Heidari S, Shahrami B, Rad S, et al. 2026; Support Care Cancer.•DOI: 10.1007/s00520-026-10434-2
Immune function / cold duration
Moderate
Population: Adults with common cold
Study type: Randomized Controlled Trial
Dose context: 1000 mg typical (range: 1000–2000 mg) • Duration: 14 days

Vitamin C supplementation was associated with a reduction in the duration of cold symptoms by approximately 8% in adults.

Citation: Hemilä H, Chalker E. 2013; Cochrane Database Syst Rev.•DOI: 10.1002/14651858.CD000980.pub4
Collagen synthesis / skin aging
High
Population: Middle-aged women
Study type: Randomized Controlled Trial
Dose context: 500 mg typical (range: 500–1000 mg) • Duration: 12 weeks

Supplementation with Vitamin C improved skin elasticity and reduced wrinkles, likely due to enhanced collagen synthesis.

Citation: Pullar JM, Carr AC, Vissers MC. 2017; Nutrients.•DOI: 10.3390/nu9020086

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