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Athletic Performance and Recovery

Combining L-Citrulline with Electrolytes can enhance athletic performance and support recovery. L-Citrulline improves nitric oxide production and endurance, while Electrolytes support hydration and muscle function.

What this is for
General support
performance, recovery, endurance
Why you are seeing this
Goal fit: performance, recovery, endurance.
What to do next
Add body metrics if you want dose previews to reflect your weight rather than the reference dose.
PublicBuilt 20 Apr 20262 ingredientsNo interactions detected
Core stack
The main ingredients doing the work.
2 key items
L-CitrullineModerate
30 min pre-workout
L-Citrulline improves nitric oxide production and endurance.
6000mg
Cardiovascular health
Moderate
Population: General population
Study type: Systematic review and meta-analysis
Dose context: 6000 mg typical

L-Citrulline showed moderate evidence for reducing cardiovascular risk factors.

Citation: Makama et al. (2025). L-Arginine and L-Citrulline for Prevention and Treatment of Pre-Eclampsia: A Systematic Review and Meta-Analysis.DOI: 10.1111/1471-0528.18070
Endurance performance
Moderate
Population: Young adult trained males
Study type: RCT
Dose context: 6000 mg typical

L-Citrulline supplementation showed potential benefits for endurance performance.

Citation: Cabre et al. (2023). The effects of L-Citrulline and Glutathione on Endurance performance in young adult trained males.DOI: 10.1080/15502783.2023.2206386
Blood pressure
Moderate
Population: Hypertensive postmenopausal women
Study type: Systematic review
Dose context: 6000 mg typical

L-Citrulline supplementation improved endothelial function & reduced blood pressure.

Citation: Maharaj et al. (2022). Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.DOI: 10.3390/nu14204396
During workout
Electrolytes support hydration and muscle function.
0mg
Trade-offs & context
Cardiovascular

Excess sodium can raise blood pressure — monitor if hypertensive or on a sodium-restricted diet

Interaction

Potassium supplementation interacts with ACE inhibitors and potassium-sparing diuretics — risk of dangerous hyperkalaemia

Muscle cramps & hyponatremia
High
Population:
Study type:
Dose context:

Sodium intake, both at high and low doses, has been found to be associated with health and performance issues in athletes. Besides, there have been theories that an electrolyte imbalance, specifically sodium, contributes to the development of muscle cramps (EAMC) and hyponatremia (EAH).

Citation: Perez-Lopez, Int J Environ Res Public Health, 2022, 19, 3651DOI: 10.3390/ijerph19063651https://pmc.ncbi.nlm.nih.gov/articles/PMC8955583/
Hydration / performance in heat
High
Population: Endurance athletes; workers in heat
Study type: RCTs
Dose context: 500 mg typical (range: 300–1000 mg) • Duration: Acute / during exercise

Sodium supplementation prevents hyponatraemia in prolonged exercise; maintains fluid balance & reduces cramping.

Citation: Montain et al. 2006; Lara et al. 2019https://pubmed.ncbi.nlm.nih.gov/16964742/
Sodium is the critical electrolyte for rehydration; potassium & magnesium support but less critical acutely.
Stack pre-check
No personal data connected — connect wearables or upload bloodwork for a personalised check
Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
L-Citrulline
60 min pre-workout
Tmax ~1h. Plasma nitric oxide elevation peaks 60–90 min post-ingestion. (Onset: ~1h, half-life: ~1.5h)

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

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