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Cardiovascular Health and Blood Pressure Support

Combining Red Yeast Rice with Garlic can support cardiovascular health and improve blood pressure. Red Yeast Rice is known for its cholesterol-lowering effects, while Garlic supports cardiovascular health by improving blood pressure and reducing inflammation.

What this is for
General support
cardiovascular, blood-pressure, longevity
Why you are seeing this
Goal fit: cardiovascular, blood-pressure, longevity.
What to do next
Add body metrics if you want dose previews to reflect your weight rather than the reference dose.
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Buy stack
Public•Built 20 Apr 2026•2 ingredients•No interactions detected
Core stack
The main ingredients doing the work.
2 key items
Red Yeast RiceHigh
Daily with meals •
Red Yeast Rice is known for its cholesterol-lowering effects.
Buy ingredient →
600mg
LDL cholesterol reduction
High
Population: Adults with hypercholesterolemia
Study type: Systematic review and Meta-analysis
Dose context: 1200 mg typical • Duration: 4-24 weeks

Red Yeast Rice extract significantly reduced total cholesterol and LDL cholesterol levels.

Citation: Trogkanis et al. (2024). Safety and Efficacy of the Consumption of the Nutraceutical 'Red Yeast Rice Extract' for the Reduction of Hypercholesterolemia in Humans: A Systematic Review and Meta-Analysis. Nutrients.•DOI: 10.3390/nu16101453
Lipid profile improvement
High
Population: Adults with dyslipidemia
Study type: Systematic review and Meta-analysis
Dose context: 1200 mg typical

RYR supplementation significantly lowered total cholesterol, LDL-C, and triglycerides, and increased HDL-C.

Citation: Osadnik et al. (2022). A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults. Cochrane Database of Systematic Reviews.•DOI: 10.1016/j.phrs.2022.106402
LDL cholesterol reduction
Moderate
Population: Japanese adults with mild dyslipidemia
Study type: Randomized trial
Dose context: 1200 mg typical

Low dose RYR with monacolin K lowered LDL cholesterol and blood pressure.

Citation: Minamizuka et al. (2021). Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial. International Journal of Molecular Sciences.•DOI: 10.3390/nu15122682
Garlic (Allium sativum)Moderate
Daily with meals •
Garlic supports cardiovascular health by improving blood pressure.
Buy ingredient →
1200mg
blood pressure reduction
Moderate
Population: individuals with hypertension
Study type: Systematic review
Dose context: 1200 mg typical

Garlic can reduce blood pressure, waist circumference, body mass index, LDL-c, non-HDL-c, total cholesterol, triglycerides, and inflammatory markers.

Citation: Imaizumi et al. (2023). Garlic: A systematic review of the effects on cardiovascular diseases. Critical Reviews in Food Science and Nutrition.•DOI: 10.1080/10408398.2022.2043821
antimicrobial effects
Low
Population: general population
Study type: Systematic review
Dose context: 1200 mg typical

Garlic has been used as an alternative treatment for vulvovaginal candidiasis.

Citation: Martin Lopez et al. (2015). Candidiasis (vulvovaginal). Critical Reviews in Food Science and Nutrition.•DOI: 10.1080/10408398.2021.2024131
lipid profile improvement
Low
Population: adults with hypercholesterolemia
Study type: Systematic review
Dose context: 1200 mg typical

Garlic supplements did not demonstrate a significant decrease in LDL-C compared with placebo.

Citation: Osadnik et al. (2022). A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults. Archives of Endocrinology and Metabolism.•DOI: 10.1016/j.phrs.2022.106402
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Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Garlic (Allium sativum)
Take ~1h before the intended effect window
Reaches peak plasma concentration in ~1h. Half-life ~2h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

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