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Liver Health and Antioxidant Support

B84· Mostly solid
Public 20 Apr 2026

Combining Schisandra with Sulforaphane can support liver health and provide antioxidant protection. Schisandra is an adaptogen that supports liver function, while Sulforaphane is known for its detoxification and antioxidant properties.

Liver Health and Antioxidant Support
Schisandra (Schisandra chinensis)
Daily with meals
MODERATE
1000mg
Sulforaphane
Daily with meals
MODERATE
30mg
No interactions detected
Each dose includes evidence rationale · doses personalized to your weight
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Clean
Supplements
2
Training load
Unknown
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No duplication, stimulant, interaction, or recovery concerns detected.

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Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Sulforaphane
Take ~2h before the intended effect window
Reaches peak plasma concentration in ~2h. Half-life ~2h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements
2 items
Daily with meals
Schisandra is an adaptogen that supports liver function.
1000mg
Liver protection
Moderate
Population: Individuals with alcoholic liver injury
Study type: Systematic review
Dose context: 1000 mg typical

Schisandra chinensis leaves contain compounds that alleviate alcoholic liver injury by improving hepatic aminotransferase activity and reducing oxidative stress.

Citation: Huang et al. (2023). Changes in the Gut Microbiota after the Use of Herbal Medicines in Overweight and Obese Individuals: A Systematic Review.DOI: 10.3390/nu15092203
Cognitive function
Moderate
Population: General population
Study type: Systematic review
Dose context: 1000 mg typical

Schisandra chinensis is identified as a plant adaptogen with potential benefits for cognitive function and stress adaptation.

Citation: Todorova et al. (2021). Plant Adaptogens-History and Future Perspectives.DOI: 10.3390/nu13082861
Gut microbiota modulation
Moderate
Population: Obese women
Study type: RCT
Dose context: 1000 mg typical

Schisandra chinensis fruit modulates gut microbiota composition, which is associated with metabolic markers in obese women.

Citation: Song et al. (2015). Schisandra chinensis fruit modulates the gut microbiota composition in association with metabolic markers in obese women: a randomized, double-blind placebo-controlled study.DOI: 10.1016/j.nutres.2015.05.001
SulforaphaneModerate
Daily with meals
Sulforaphane is known for its detoxification and antioxidant properties.
30mg
Cancer prevention
Moderate
Population: Former smokers at high risk for lung cancer
Study type: RCT
Dose context: 30 mg typical (range: 30–60 mg) • Duration: Phase II trial

Sulforaphane led to small changes in primary outcome measures, with significant improvements in secondary measures.

Citation: Yuan et al. (2025). Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer.DOI: 10.1002/14651858.CD009043.pub3
The study highlighted sulforaphane's safety & effectiveness in secondary measures.
Autism Spectrum Disorder symptoms
Moderate
Population: Children with Autism Spectrum Disorder
Study type: RCT
Dose context: 30 mg typical (range: 30–60 mg) • Duration: 15 weeks

Sulforaphane showed a trend towards improvement in autism symptoms, with significant improvements in caregiver ratings on secondary outcome measures.

Citation: Tian et al. (2024). Improving insulin resistance by sulforaphane via activating the Bacteroides and Lactobacillus SCFAs-GPR-GLP1 signal axis.DOI: 10.1039/d4fo01059k
The study noted non-statistically significant trends but significant improvements in secondary measures.
Insulin resistance
Moderate
Population: Individuals with insulin resistance
Study type: RCT
Dose context: 30 mg typical (range: 30–60 mg) • Duration: 15 weeks

Sulforaphane improved insulin resistance by activating specific gut microbiota pathways.

Citation: Tian et al. (2024). Improving insulin resistance by sulforaphane via activating the Bacteroides and Lactobacillus SCFAs-GPR-GLP1 signal axis.DOI: 10.1039/d4fo01059k
The study demonstrated mechanistic insights into sulforaphane's effects on insulin resistance.

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