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Schisandra (Schisandra chinensis)

Schisandra is an adaptogenic berry known for its ability to modulate cortisol levels, support liver detoxification, and reduce stress-induced cognitive decline. It is traditionally used in Chinese medicine for longevity, performance, and mental clarity.

adaptogenliver healthcognitivestressneuroprotection

Evidence last reviewed: 20 Apr 2026

Evidence
4 records
4 recordsBest grade:Moderate
Biomarkers
Cognitive FunctionPerceived StressOxidative Stress (MDA)Gut MicrobiomeALT / AST (Liver)

Schisandra has shown hepatoprotective effects and potential cognitive benefits, particularly in stress adaptation. However, the evidence is varied in strength and more high-quality studies are needed to confirm its efficacy across different populations.

Cognitive function
General population · Systematic review
Moderate

Schisandra chinensis is identified as a plant adaptogen with potential benefits for cognitive function and stress adaptation.

Dose: 1000 mgForm: Extract
Liver protection
Individuals with alcoholic liver injury · Systematic review
Moderate

Schisandra chinensis leaves contain compounds that alleviate alcoholic liver injury by improving hepatic aminotransferase activity and reducing oxidative stress.

Dose: 1000 mgForm: Tea
Gut microbiota modulation
Obese women · RCT
Moderate

Schisandra chinensis fruit modulates gut microbiota composition, which is associated with metabolic markers in obese women.

Dose: 1000 mgForm: Fruit
Hepatoprotective effects
Individuals with liver injury · Review
Low

Schisandra chinensis polysaccharides exhibit liver protective and anti-inflammatory activities.

Dose: 1000 mgForm: Polysaccharides
Stacks containing Schisandra (Schisandra chinensis)
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liver-healthantioxidantdetoxification

Combining Schisandra with Sulforaphane can support liver health and provide antioxidant protection. Schisandra is an adaptogen that supports liver function, while Sulforaphane is known for its detoxification and antioxidant properties.

Schisandra (Schisandra chinensis)
1000mg
Sulforaphane
30mg
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Forms & usage
How to take it

Take 500-1000 mg daily, preferably with meals.

Extract
Commonly used in supplements for its concentrated active compounds.
Tea
Made from dried leaves, used for its hepatoprotective effects.
Capsule
Convenient form for standardized dosing.
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