Sulforaphane
Sulforaphane is an isothiocyanate derived from broccoli sprouts that activates the Nrf2 pathway, promoting antioxidant & detoxification processes. It shows potential benefits for cancer prevention, autism spectrum disorder, & cardiovascular protection.
Evidence last reviewed: 05 Apr 2026
The evidence for sulforaphane is moderate, showing potential benefits for autism symptoms, insulin resistance, and cancer prevention. However, the studies have small sample sizes and varying outcomes, indicating a need for further research.
Insulin resistanceIndividuals with insulin resistance · RCTModerate
Sulforaphane improved insulin resistance by activating specific gut microbiota pathways.
Cancer preventionFormer smokers at high risk for lung cancer · RCTModerate
Sulforaphane led to small changes in primary outcome measures, with significant improvements in secondary measures.
Autism Spectrum Disorder symptomsChildren with Autism Spectrum Disorder · RCTModerate
Sulforaphane showed a trend towards improvement in autism symptoms, with significant improvements in caregiver ratings on secondary outcome measures.
Liver Health and Antioxidant Support
Combining Schisandra with Sulforaphane can support liver health and provide antioxidant protection. Schisandra is an adaptogen that supports liver function, while Sulforaphane is known for its detoxification and antioxidant properties.
Forms & usage▾
Take 100-200 mg daily, preferably with food.