StackTerminal.Health

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Liver Health and Detoxification Support

B84· Mostly solid
Public 20 Apr 2026

Combining N-Acetyl Cysteine with Dandelion Root can support liver health and detoxification. N-Acetyl Cysteine is a precursor to glutathione, a key antioxidant for liver health, while Dandelion Root promotes bile production and liver detoxification.

Liver Health and Detoxification Support
N-Acetyl Cysteine (NAC)
Daily with meals
MODERATE
600mg
Dandelion Root
Daily with meals
MODERATE
2000mg
No interactions detected
Each dose includes evidence rationale · doses personalized to your weight
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Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

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Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
N-Acetyl Cysteine (NAC)
Take ~1.5h before the intended effect window
Reaches peak plasma concentration in ~1.5h. Half-life ~5.6h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements
2 items
Daily with meals
N-Acetyl Cysteine is a precursor to glutathione, a key antioxidant for liver health.
600mg
Cannabis use disorder
Moderate
Population: Patients with cannabis use disorder
Study type: Systematic review
Dose context: 1800 mg typical

NAC showed promising results in reducing cannabis use & craving.

Citation: Papi et al. (2024). N-acetylcysteine Treatment in Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis/Pre-COPD: Distinct Meta-analyses. Journal of Neurobiology.DOI: 10.1016/j.arbres.2024.03.010
Psychiatric disorder symptoms
Moderate
Population: Patients with psychiatric disorders
Study type: Systematic review
Dose context: 1800 mg typical

NAC showed favorable evidence for use in several psychiatric & neurological disorders.

Citation: Sharma et al. (2022). N-acetyl cysteine in the treatment of cannabis use disorder: A systematic review of clinical trials. Journal of Gerontology.DOI: 10.1016/j.addbeh.2022.107283
Glutathione levels
High
Population: Older adults
Study type: RCT
Dose context: 1800 mg typical • Duration: 16 weeks

GlyNAC supplementation improved glutathione deficiency & oxidative stress.

Citation: Kumar et al. (2023). Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial. Journal of Gerontology.DOI: 10.1093/gerona/glac135
Daily with meals
Dandelion Root promotes bile production and liver detoxification.
2000mg
Liver support
Very low
Population: General population
Study type: Case series
Dose context: 2000 mg typical (range: 2000–4000 mg)

Dandelion root is traditionally used for liver detoxification, though clinical evidence is limited.

Citation: Traditional use and pharmacological data.
No clinical trials available.
Diuretic effects
Very low
Population: General population
Study type: Case series
Dose context: 2000 mg typical (range: 2000–4000 mg)

Dandelion root is used for its diuretic properties, but lacks robust clinical evidence.

Citation: Traditional use and pharmacological data.
No clinical trials available.
Anti-inflammatory activity
Very low
Population: General population
Study type: Case series
Dose context: 2000 mg typical (range: 2000–4000 mg)

Preliminary evidence suggests anti-inflammatory effects, but clinical data is lacking.

Citation: Traditional use and pharmacological data.
No clinical trials available.

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