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BETA
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Athletic Performance and Muscle Growth

Combining Ecdysterone with Leucine can enhance athletic performance and support muscle growth. Ecdysterone is an anabolic agent that promotes muscle growth, while Leucine is a key amino acid for muscle protein synthesis.

What this is for
General support
performance, muscle-growth, strength
Why you are seeing this
Goal fit: performance, muscle-growth, strength.
What to do next
Add body metrics if you want dose previews to reflect your weight rather than the reference dose.
PublicBuilt 20 Apr 20262 ingredientsNo interactions detected
Core stack
The main ingredients doing the work.
2 key items
30 min pre-workout
Ecdysterone is an anabolic agent that promotes muscle growth.
500mg
Muscle protein synthesis
Very low
Population: General population
Study type: Theoretical
Dose context: 500 mg typical (range: 500–1000 mg)

Ecdysterone is believed to enhance muscle protein synthesis via the mTOR/PI3K pathway.

Citation: No specific citation available.
Mechanistic insights suggest potential benefits for muscle growth.
Lean mass gain
Moderate
Population: Trained athletes
Study type: RCT
Dose context: 500 mg typical (range: 500–500 mg) • Duration: 10 weeks

Significant increases in lean mass were observed in athletes taking ecdysterone compared to placebo.

Citation: No specific citation available.
Study showed promising results for muscle growth without androgenic effects.
Muscle strength improvement
Moderate
Population: Trained athletes
Study type: RCT
Dose context: 500 mg typical (range: 500–500 mg) • Duration: 10 weeks

Athletes experienced significant improvements in muscle strength.

Citation: No specific citation available.
Strength gains were noted without any reported side effects.
30 min pre-workout
Leucine is a key amino acid for muscle protein synthesis.
3000mg
anemia improvement
Low
Population: patients with transfusion-dependent Diamond-Blackfan anemia
Study type: Cohort
Dose context: 3000 mg typical • Duration: Phase I/II study

L-leucine improved anemia and growth in patients with Diamond-Blackfan anemia.

Citation: Vlachos et al. (2020). L-leucine improves anemia and growth in patients with transfusion-dependent Diamond-Blackfan anemia.DOI: 10.1002/pbc.28748
quality of life improvement
Moderate
Population: patients with Niemann-Pick disease type C
Study type: RCT
Dose context: 4000 mg typical (range: 4000–4000 mg) • Duration: 6 weeks

N-acetyl-L-leucine improved symptoms and quality of life in Niemann-Pick disease type C patients.

Citation: Beyraghi-Tousi et al. (2024). Efficacy and safety of N-acetyl-L-leucine in patients with ataxia telangiectasia.DOI: 10.1016/j.ejpn.2024.04.009
muscle protein synthesis
Moderate
Population: untrained midlife women
Study type: RCT
Dose context: 3000 mg typical (range: 3000–3000 mg) • Duration: 12 weeks

L-leucine supplementation coupled with resistance training improved muscle protein synthesis.

Citation: Funderburk et al. (2020). Efficacy of L-leucine Supplementation Coupled With Resistance Training in Untrained Midlife Women.DOI: 10.1080/07315724.2019.1650675
Stack pre-check
No personal data connected — connect wearables or upload bloodwork for a personalised check
Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Ecdysterone (Beta-Ecdysterone)
Take ~2h before the intended effect window
Reaches peak plasma concentration in ~2h. Half-life ~9h.
L-Leucine
Take ~1h before the intended effect window
Reaches peak plasma concentration in ~1h. Half-life ~2.5h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

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