StackTerminal.Health

BETA

Cognitive & Energy Enhancement

Public 06 Apr 2026

Modafinil & methylene blue are combined to enhance cognitive function & energy levels. Modafinil is a wakefulness-promoting agent that improves focus, while methylene blue supports mitochondrial function & cognitive performance.

Cognitive & Energy Enhancement
Modafinil
Morning
MODERATE
100mg
Methylene Blue
Morning
MODERATE
2mg
No interactions detected
Each dose includes evidence rationale · doses personalized to your weight
AI risk assessment
Context: No wearable data
PROAI risk assessment is available with Pro.
See plans
Stack pre-check
No personal data connected — connect wearables or upload bloodwork for a personalised check
Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Modafinil
Take ~2h before the intended effect window
Reaches peak plasma concentration in ~2h. Half-life ~12h.
Methylene Blue
Take ~1h before the intended effect window
Reaches peak plasma concentration in ~1h. Half-life ~5h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements
2 items
Morning
Promotes wakefulness & improves focus.
100mg
Wakefulness
High
Population: Adults with narcolepsy
Study type: Systematic review
Dose context: 200 mg typical

Modafinil is effective in promoting wakefulness in patients with narcolepsy.

Citation: Bassetti et al. (2021). European guideline and expert statements on the management of narcolepsy in adults and children. BMJ.DOI: 10.1136/bmj.d5928
Treatment of stimulant use disorder
Moderate
Population: Adults with amphetamine-type stimulant use disorder
Study type: Systematic review and meta-analysis
Dose context: 200 mg typical

Modafinil showed efficacy in the treatment of amphetamine-type stimulant use disorder.

Citation: Elkrief et al. (2024). Efficacy and Safety of Modafinil for Treatment of Amphetamine-Type Stimulant Use Disorder: A Systematic Review and Meta-Analysis. Journal.DOI: 10.1177/1087054717720719
Cognitive enhancement
Moderate
Population: Adults with treatment-resistant depression
Study type: Systematic review
Dose context: 200 mg typical

Modafinil showed significant efficacy in cognitive enhancement compared to placebo.

Citation: Repantis et al. (2021). Cognitive enhancement effects of stimulants: a randomized controlled trial testing methylphenidate, modafinil, and caffeine. BMJ.DOI: 10.1136/bmj.k4218
Morning
Supports mitochondrial function & cognitive performance.
2mg
Mortality reduction
Low
Population: Critically ill and perioperative patients
Study type: Meta-analysis
Dose context: 2 mg typical

Methylene Blue may reduce mortality in critically ill & perioperative patients.

Citation: Pruna et al. (2024). Methylene Blue Reduces Mortality in Critically Ill and Perioperative Patients: A Meta-Analysis of Randomized Trials. New England Journal of Medicine.DOI: 10.1056/NEJMra1208623
Cognitive enhancement
Very low
Population: General population
Study type: Theoretical
Dose context: 2 mg typical (range: 2–10 mg)

Methylene Blue is theorized to enhance cognitive function through its role as a mitochondrial electron shuttle.

Citation: Based on known pharmacology.
No direct clinical evidence available.
Neuroprotection
Very low
Population: General population
Study type: Theoretical
Dose context: 2 mg typical (range: 2–10 mg)

Methylene Blue is theorized to offer neuroprotective benefits due to its antioxidant properties.

Citation: Based on known pharmacology.
No direct clinical evidence available.
My experience with this stack
Share what worked, what did not, & help improve this protocol.

Discussion

No comments yet. Be the first to add context or ask a question.
Max 500 characters

Similar community stacks

Avoid reinventing the wheel: fork a community stack that matches your category tags, then edit it.

Browse all community stacks →
cognitiveenergyfocus

Adderall & acetyl-l-carnitine are combined to support cognitive function & enhance energy levels. Adderall is a stimulant that improves focus & cognitive performance, while acetyl-l-carnitine supports mitochondrial function & energy production.

Adderall (Amphetamine Salts)
10mg
Acetyl-L-Carnitine
1000mg
New
View
focuscognitivecaffeine-free

Supports focus & mental clarity without stimulants.

L-Theanine
200mg
L-Tyrosine
1000mg
New
View
cognitivemoodfocus

Aniracetam & bacopa monnieri are combined to support cognitive function & enhance mood. Aniracetam is known for its anxiolytic & cognitive-enhancing effects, while bacopa monnieri supports memory & reduces anxiety.

Aniracetam
1000mg
Bacopa Monnieri
300mg
New
View