Enhanced Cognitive Performance

B84· Mostly solid

Public • 20 Apr 2026

Combining DMAE with Uridine Monophosphate can enhance cognitive function and focus. DMAE is known for its role in improving attention and mental clarity, while Uridine supports neuroplasticity and cognitive enhancement.

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Enhanced Cognitive Performance

cognitive focus nootropic

DMAE (Dimethylaminoethanol)

Morning

MODERATE

350mg

Uridine Monophosphate

Morning

MODERATE

500mg

No interactions detected

Each dose includes evidence rationale · doses personalized to your weight

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Supplements

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Unknown

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No duplication, stimulant, interaction, or recovery concerns detected.

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Interaction Analysis

Pharmacokinetic + pair-level checks

Timing optimizations

DMAE (Dimethylaminoethanol)

Take ~2h before the intended effect window

Reaches peak plasma concentration in ~2h. Half-life ~3h.

Uridine Monophosphate

Take ~2h before the intended effect window

Reaches peak plasma concentration in ~2h. Half-life ~3h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements

2 items

DMAE (Dimethylaminoethanol)Moderate

Morning •

DMAE enhances attention and mental clarity.

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350mg

skin firming

Moderate

Population: general population with aging skin

Study type: RCT

Dose context: 350 mg typical • Duration: 16 weeks

3% DMAE facial gel applied daily improved skin firmness.

Citation: Grossman et al. (2005). The role of dimethylaminoethanol in cosmetic dermatology. Journal.•DOI: 10.2165/00128071-200506010-00005

cognitive function

Moderate

Population: subjects with threshold emotional disturbance

Study type: RCT

Dose context: 350 mg typical • Duration: 12 weeks

DMAE-containing supplement reduced theta and alpha1 power in EEG, indicating potential cognitive benefits.

Citation: Dimpfel et al. (2003). Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional states. Journal.•DOI: 10.1034/j.1600-0846.2002.10295.x

skin tensile effect

Moderate

Population: general population

Study type: RCT

Dose context: 350 mg typical

DMAE gel showed a significant cutaneous tensile effect compared to placebo.

Citation: Uhoda et al. (2002). Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel. Journal.•DOI: 10.1034/j.1600-0846.2002.10295.x

Uridine MonophosphateLow

Morning •

Uridine supports neuroplasticity and cognitive enhancement.

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500mg

Cognitive function

Low

Population: Patients with Alzheimer's disease

Study type: Systematic review

Dose context: 500 mg typical

Preliminary evidence suggests that uridine monophosphate, as part of a multinutrient combination, may support cognitive function in Alzheimer's disease.

Citation: Engelborghs et al. (2014). Rationale and clinical data supporting nutritional intervention in Alzheimer's disease. Journal.•DOI: 10.1179/0001551213Z.0000000006

Part of a multinutrient intervention.

Pain reduction

Low

Population: Patients with peripheral entrapment neuropathy

Study type: Cohort

Dose context: 500 mg typical • Duration: 2 months

Uridine monophosphate, combined with folic acid and vitamin B12, reduced pain scores in patients with peripheral entrapment neuropathy.

Citation: Negrão et al. (2016). Uridine monophosphate, folic acid and vitamin B12 in patients with symptomatic peripheral entrapment neuropathies. Journal.•DOI: 10.2217/pmt.15.60

Neuroprotection

Low

Population: Patients with Alzheimer's disease

Study type: Systematic review

Dose context: 500 mg typical

Uridine monophosphate, as part of a multinutrient formula, may contribute to neuroprotection in Alzheimer's disease.

Citation: Rijpma et al. (2015). Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease. Journal.•DOI: 10.1186/s13195-015-0134-1

Part of a multinutrient intervention.

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