Vitex agnus-castus
Herbal used for PMS symptom relief; evidence includes RCTs & systematic reviews, though products/extracts vary widely.
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Placebo-controlled RCT reported improved PMS symptom scores with Vitex preparations; extract standardization matters.
Meta-analysis of 3 high-quality double-blind RCTs (n=520) meeting CONSORT criteria found women taking Vitex agnus-castus were 2.57 times more likely to experience PMS symptom remission vs placebo (OR 2.57, 95% CI 1.52–4.35). Majority of trials are excluded due to incomplete reporting.
Stacks containing Vitex agnus-castus
Public community stacks that include this ingredient.
PMS Calmer (Low-Stim, Cycle-Friendly)
Cycle-phase support focused on calm & sleep quality without stimulants.
This stack addresses the key nutritional & hormonal drivers of female fertility. Folate is essential for DNA synthesis & embryo development. Myo-inositol is the most evidence-backed intervention for improving ovarian function, egg quality, & cycle regularity — particularly in PCOS. CoQ10 restores mitochondrial energy in aging oocytes, & Vitex supports luteal phase adequacy through LH modulation.
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