Vitex agnus-castus
Herbal used for PMS symptom relief; evidence includes RCTs and systematic reviews, though products/extracts vary widely.
womens-healthpmsstress-anxietysleep
Dosing model
FLATFixed dose (no body-weight scaling).
Min dose
20 mg
Max dose
40 mg
Rounding
5 mg
Stacks containing Vitex agnus-castus
Public community stacks that include this ingredient.
sleepwomens-health
PMS Calmer (Low-Stim, Cycle-Friendly)
by@athlete
Cycle-phase support focused on calm and sleep quality without stimulants.
Vitex agnus-castus
20mg
Glycine
3000mg
L-Theanine
200mg
New
Evidence
2 records
PMS symptom reduction
Women with PMS • RCT
Placebo-controlled RCT reported improved PMS symptom scores with Vitex preparations; extract standardization matters.
Dose: 20 mg • Duration: 2–3 cycles (varies by RCT)
PMS symptom remission — meta-analysis of double-blind RCTs
Women with PMS • Meta-analysis of double-blind RCTs
Meta-analysis of 3 high-quality double-blind RCTs (n=520) meeting CONSORT criteria found women taking Vitex agnus-castus were 2.57 times more likely to experience PMS symptom remission vs placebo (OR 2.57, 95% CI 1.52–4.35). Majority of trials are excluded due to incomplete reporting.
Dose: 20 mg • Duration: 3 menstrual cycles
Forms
Capsule
Extract-specific dosing varies by product