Berberine
Alkaloid from Berberis plants with evidence for glycemic control and lipid improvement.
Stacks containing Berberine
Public community stacks that include this ingredient.
Longevity & Metabolic Health Base
Foundational stack aimed at mitochondrial function, insulin sensitivity, and long-term healthspan.
Berberine-derived stack
Targets glucose and lipid markers for long-term metabolic health.
Metabolic Health Base
Targets glucose and lipid markers for long-term metabolic health.
Berberine reduced fasting plasma glucose by 0.82 mmol/L, HbA1c by 0.63%, and 2-hour postprandial glucose by 1.16 mmol/L across 37 RCTs (n=3048); glucose-lowering effect correlated with baseline glucose levels.
Berberine reduced LDL cholesterol by 0.46 mmol/L, triglycerides by 0.34 mmol/L, and total cholesterol by 0.48 mmol/L across 18 RCTs; HDL changes differed by sex (increase in women, slight decrease in men). No serious adverse events reported.