StackTerminal.Health

BETA

Urolithin A

Gut-derived metabolite from ellagic acid; activates mitophagy. Promising longevity & muscle endurance data.

longevityendurancerecoverymetabolic

Evidence last reviewed: 04 Apr 2026

Evidence
1 record
1 recordBest grade:Moderate
Biomarkers
Muscle Endurance

Research shows moderate evidence for Urolithin A's benefits in muscle endurance and mitochondrial function, particularly in older adults. However, the studies are short-term, and more extensive research is needed to confirm long-term safety and efficacy.

Muscle endurance / mitochondrial health
Older adults; healthy middle-aged adults · RCTs (phase I/II)
Moderate

Improved handgrip & leg muscle endurance; mitophagy markers improved; good safety profile.

Dose: 500 mgDuration: 4–12 weeks
~40% of people are 'non-producers' from gut microbiome; direct supplementation bypasses this.
Stacks containing Urolithin A
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endurancerecoverydaily

Built from your profile goals, constraints, & current training/recovery context. This stack includes evidence-backed supplements selected for practical fit, & you can fine-tune doses & timing in edit mode.

Spirulina
6000mg
Urolithin A
500mg
Fish Oil
2000mg
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endurancemens-healthconstraints

This personalized supplement stack is optimized for enhancing your baseline health, supporting recovery, and boosting strength during your active training phase. With Vitamin D3 for immune support, electrolytes for hydration, fish oil for overall wellness, creatine for power, and tart cherry for recovery, this budget-friendly combination will help you maintain peak performance and promote effective recovery.

Vitamin D3
1000mg
Electrolytes (Sodium / Potassium / Magnesium blend)
1000mg
Fish Oil
2000mg
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Community Insights
Forms & usage
How to take it

Take 250-500 mg daily, preferably with food.

Urolithin A (Mitopure)
Standardised form used in most trials.
Safety & trade-offs1
Note

Limited long-term human safety data — trials up to 4 months only

High  Moderate   Low / note

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