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Passionflower

Passionflower is an anxiolytic herb known for its GABA-A modulating properties, used to alleviate generalized anxiety, insomnia, & symptoms of opioid withdrawal.

anxietysleepstressrelaxation

Evidence last reviewed: 05 Apr 2026

Evidence
5 records
5 recordsBest grade:Moderate
Biomarkers
Sleep Quality (subjective)AnxietyPerceived Stress

The evidence for passionflower shows moderate effectiveness in reducing anxiety and stress, with some support for sleep improvement. However, studies often involve small sample sizes, limiting the strength of conclusions.

Anxiety reduction
Adults with anxiety disorders · Systematic review
Moderate

Passionflower preparations were found to reduce anxiety levels, with effects less evident in mild anxiety.

Dose: 500 mg
Opioid withdrawal symptom reduction
Patients undergoing opioid withdrawal · Systematic review
Low

Passionflower may aid in reducing symptoms of opioid withdrawal.

Dose: 500 mg
Stress reduction
Adults with stress-related disorders · Systematic review
Moderate

Passionflower helps reduce stress & can be helpful in treating insomnia, anxiety, & depression.

Dose: 500 mg
Sleep improvement
Subjects with insomnia disorder · Systematic review
Low

Passionflower may benefit the treatment of insomnia, though evidence is limited by small sample sizes.

Dose: 500 mg
Anxiety reduction
Generalized anxiety disorder patients · RCT
Moderate

Passionflower extract was comparable to oxazepam in reducing anxiety symptoms.

Dose: 500 mgForm: Extract
Stacks containing Passionflower
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sleeprelaxationcalm

Valerian root & passionflower are combined to aid sleep & promote relaxation. Valerian root is known for its calming effects, while passionflower helps reduce anxiety & improve sleep quality.

Valerian Root
600mg
Passionflower
500mg
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sleeprelaxationcalm

Combining Tryptophan with Passionflower can enhance sleep quality and promote relaxation. Tryptophan is a precursor to serotonin and melatonin, supporting sleep, while Passionflower is known for its calming effects.

L-Tryptophan
1000mg
Passionflower
500mg
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Community Insights
Forms & usage
How to take it

Take 250-500 mg of passionflower extract once daily, preferably in the evening.

Extract
Commonly used in supplements for anxiety and sleep.
Tea
Traditional form for calming effects.
Capsule
Standardized doses for convenience.
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