StackTerminal.Health

BETA

L-Citrulline

L-Citrulline is a non-essential amino acid that enhances nitric oxide production, which can improve blood flow, reduce muscle soreness, & boost endurance performance, particularly in athletes.

nitric oxideperformanceendurancerecovery

Evidence last reviewed: 05 Apr 2026

Evidence
5 records
5 recordsBest grade:Moderate
Biomarkers
Blood Pressure

The evidence for L-Citrulline shows moderate benefits for endurance performance and blood pressure reduction, particularly in specific populations. However, some studies indicate no significant effects on exercise performance in the general population, highlighting the need for more targeted research.

Cardiovascular health
General population · Systematic review and meta-analysis
Moderate

L-Citrulline showed moderate evidence for reducing cardiovascular risk factors.

Dose: 6000 mg
Endurance performance
Young adult trained males · RCT
Moderate

L-Citrulline supplementation showed potential benefits for endurance performance.

Dose: 6000 mg
Exercise performance
General population · Systematic review and meta-analysis
Low

No significant effect on exercise performance was found following L-citrulline supplementation.

Dose: 6000 mg
Blood pressure
Hypertensive postmenopausal women · Systematic review
Moderate

L-Citrulline supplementation improved endothelial function & reduced blood pressure.

Dose: 6000 mg
Blood pressure
Middle-aged and older adults · Systematic review and meta-analysis
Moderate
Stacks containing L-Citrulline
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performanceendurancestrength

Betaine anhydrous & l-citrulline are combined to enhance athletic performance & endurance. Betaine anhydrous supports strength & power, while l-citrulline aids in nitric oxide production, improving blood flow & endurance.

Betaine Anhydrous
2500mg
L-Citrulline
6000mg
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performancerecoveryendurance

Combining L-Citrulline with Electrolytes can enhance athletic performance and support recovery. L-Citrulline improves nitric oxide production and endurance, while Electrolytes support hydration and muscle function.

L-Citrulline
6000mg
Electrolytes (Sodium / Potassium / Magnesium blend)
0mg
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Community Insights
Forms & usage
How to take it

Take 6–8 grams daily, ideally 30–60 minutes before exercise.

Powder
Commonly mixed with water or juice for easy consumption.
Capsule
Convenient for precise dosing.
My notes
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