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Blood Sugar Regulation and Metabolic Health

Combining Gymnema Sylvestre with Bitter Melon can support blood sugar regulation and metabolic health. Gymnema Sylvestre reduces sugar absorption, while Bitter Melon improves insulin sensitivity.

What this is for
General support
blood-sugar, metabolic, weight-management
Why you are seeing this
Goal fit: blood-sugar, metabolic, weight-management.
What to do next
Add body metrics if you want dose previews to reflect your weight rather than the reference dose.
PublicBuilt 20 Apr 20262 ingredientsNo interactions detected
Core stack
The main ingredients doing the work.
2 key items
Daily with meals
Gymnema Sylvestre reduces sugar absorption.
300mg
body weight
Moderate
Population: obese patients
Study type: Randomized Study
Dose context: 400 mg typical • Duration: 3 months

Gymnema Sylvestre decreased body weight & improved metabolic parameters.

Citation: Bandala et al. (2024). Comparative Effects of Gymnema sylvestre and Berberine on Adipokines, Body Composition, and Metabolic Parameters in Obese Patients: A Randomized Study. Journal.DOI: 10.3390/nu16142284
lipid profile
Moderate
Population: adults
Study type: Systematic review
Dose context: 400 mg typical

Gymnema Sylvestre supplementation may improve lipid profiles.

Citation: Zamani et al. (2023). The effects of Gymnema Sylvestre supplementation on lipid profile, glycemic control, blood pressure, and anthropometric indices in adults: A systematic review and meta-analysis. Journal.DOI: 10.1002/ptr.7585
insulin sensitivity
Moderate
Population: patients with impaired glucose tolerance
Study type: RCT
Dose context: 600 mg typical (range: 600–600 mg) • Duration: 12 weeks

Gymnema Sylvestre improved insulin sensitivity & secretion.

Citation: Gaytán Martínez et al. (2021). Effect of Gymnema sylvestre Administration on Glycemic Control, Insulin Secretion, and Insulin Sensitivity in Patients with Impaired Glucose Tolerance. Journal.DOI: 10.26226/morressier.5d9b6232ea541d6ca8494081
Bitter MelonModerate
Daily with meals
Bitter Melon improves insulin sensitivity.
1000mg
lipid-profile
Moderate
Population: adults with dyslipidemia
Study type: Systematic review
Dose context: 1000 mg typical

Bitter melon consumption resulted in a significant decrease in plasma triglycerides & LDL cholesterol.

Citation: Guarneiri et al. (2025). Investigation of the Influence of a Bitter Melon Product on Indicators of Cardiometabolic Health in Adults with Prediabetes. Journal.DOI: 10.1080/27697061.2024.2428301
blood-glucose
Low
Population: patients with type 2 diabetes
Study type: Review
Dose context: 1000 mg typical

Bitter melon has a moderate hypoglycemic effect, though studies were small & not randomized.

Citation: Leung et al. (2009). Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): a mini review. Journal.DOI: 10.1017/S0007114509992054
blood-glucose
Moderate
Population: patients with type 2 diabetes
Study type: RCT
Dose context: 1000 mg typical (range: 1000–2000 mg) • Duration: 12 weeks

Bitter melon significantly lowered fasting glucose levels compared to placebo.

Citation: Amini et al. (2024). The Effects of Bitter Melon (Mormordica charantia) on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal.DOI: 10.1002/ptr.8357
Stack pre-check
No personal data connected — connect wearables or upload bloodwork for a personalised check
Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
No interactions detected
No known absorption conflicts, pharmacokinetic conflicts, or synergies found between the ingredients in this stack.

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