Cognitive & Antioxidant Support

Public • 06 Apr 2026

Ginkgo biloba & pterostilbene are combined to support cognitive function & provide antioxidant benefits. Ginkgo biloba improves cerebral blood flow & cognitive performance, while pterostilbene offers antioxidant support for brain health.

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cognitive antioxidant focus

Ginkgo Biloba

Daily with food

MODERATE

120mg

Pterostilbene

Daily with food

MODERATE

200mg

No interactions detected

Each dose includes evidence rationale · doses personalized to your weight

AI risk assessment

Context: No wearable data

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Stack pre-check

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1 caution

Supplements

Training load

Unknown

Caution

Ginkgo: anticoagulant risk

Ginkgo biloba prolongs bleeding time. Avoid combining with blood thinners, NSAIDs at high doses, or in the 2 weeks before surgery.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis

Pharmacokinetic + pair-level checks

Timing optimizations

Ginkgo Biloba

Take ~1.5h before the intended effect window

Reaches peak plasma concentration in ~1.5h. Half-life ~4.5h.

Pterostilbene

Take ~1h before the intended effect window

Reaches peak plasma concentration in ~1h. Half-life ~2.5h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements

2 items

Ginkgo BilobaModerate

Daily with food •

Improves cerebral blood flow & cognitive performance.

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120mg

Trade-offs & context

Interaction

Inhibits platelet aggregation — clinically significant bleeding risk with anticoagulants (warfarin, aspirin, clopidogrel)

Neural

May lower seizure threshold — avoid with epilepsy medications

Tolerance

Headache and GI upset common in first weeks of use

Cognitive performance / dementia prevention

Moderate

Population: Older adults; mild cognitive impairment

Study type: Meta-analyses (mixed quality)

Dose context: 240 mg typical (range: 120–240 mg) • Duration: 12–24 weeks

Modest improvements in attention & memory in older adults; prevention of dementia not established in large trials.

Citation: Weinmann et al. 2010 (Cochrane); Tan et al. 2015•DOI: 10.1038/ncomms1143

May increase bleeding risk; caution with anticoagulants.

PterostilbeneLow

Daily with food •

Offers antioxidant support for brain health.

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200mg

NAD+ levels

Low

Population: patients with acute kidney injury

Study type: RCT

Dose context: 250 mg typical

NRPT increased NAD+ levels in patients with acute kidney injury.

Citation: Simic et al. (2020). Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury. PNAS.•https://pubmed.ncbi.nlm.nih.gov/32791973/

muscle regeneration

Moderate

Population: elderly individuals with muscle injury

Study type: RCT

Dose context: 200 mg typical (range: 200–200 mg) • Duration: 2 weeks

Supplementation with pterostilbene & nicotinamide riboside improved muscle stem cell function & muscle regeneration.

Citation: Jensen et al. (2022). A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals. JCI Insight.•DOI: 10.1172/jci.insight.158314

anticancer activity

Low

Population: various cancer types

Study type: Systematic review

Dose context: 250 mg typical

Pterostilbene showed significant anticancer activity through apoptosis induction, cell cycle arrest, & inhibition of angiogenesis.

Citation: Fels et al. (2022). Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301. Science.•DOI: 10.1126/science.aac4854

The study highlights pterostilbene's potential in cancer treatment.

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