StackTerminal.Health

BETA
Alternative layoutGrade B · 84Clean

Gut Health & Immunity

Akkermansia muciniphila & bifidobacterium longum are combined to support gut health & boost immunity. Akkermansia muciniphila is a beneficial gut bacterium that supports the gut lining, while bifidobacterium longum enhances gut microbiota diversity & immune function.

What this is for
General support
gut-health, immune, microbiome
Why you are seeing this
Goal fit: gut-health, immune, microbiome.
What to do next
Add body metrics if you want dose previews to reflect your weight rather than the reference dose.
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Public•Built 06 Apr 2026•2 ingredients•No interactions detected
Core stack
The main ingredients doing the work.
2 key items
Akkermansia MuciniphilaModerate
Daily with food •
Supports the gut lining & overall gut health.
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0mg
Body weight & fat mass
Moderate
Population: Overweight/obese type 2 diabetes patients
Study type: RCT
Dose context: — • Duration: 12 weeks

Akkermansia muciniphila supplementation led to significant reductions in body weight & fat mass in participants with low baseline levels of the bacterium.

Citation: Zhang et al. (2025). Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut. Cell Metabolism.•DOI: 10.1016/j.cmet.2024.12.010
Efficacy was dependent on baseline levels of Akkermansia muciniphila.
Insulin sensitivity
Moderate
Population: Overweight/obese insulin-resistant volunteers
Study type: RCT
Dose context: — • Duration: 12 weeks

Supplementation with Akkermansia muciniphila improved insulin sensitivity & was well-tolerated.

Citation: Depommier et al. (2019). Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Nature Medicine.•DOI: 10.1038/s41591-019-0495-2
Muscle strength & function
Moderate
Population: General population
Study type: RCT
Dose context: — • Duration: 12 weeks

Pasteurized Akkermansia muciniphila improved muscle strength & function.

Citation: Kang et al. (2024). Pasteurized Akkermansia muciniphila HB05 (HB05P) Improves Muscle Strength and Function: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.•DOI: 10.3390/nu16234037
Bifidobacterium LongumLow
Daily with food •
Enhances gut microbiota diversity & boosts immune function.
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0mg
Depression scores & brain activity
Low
Population: Patients with irritable bowel syndrome
Study type: Pilot study
Dose context: —

Bifidobacterium longum NCC3001 reduced depression scores & altered brain activity.

Citation: Pinto-Sanchez et al. (2017). Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome. The Lancet.•DOI: 10.3410/f.727592617.793533502
Anxiety & depression
Moderate
Population: Patients with IBS and mild to moderate anxiety and/or depression
Study type: RCT
Dose context: — • Duration: 6 weeks

Bifidobacterium longum reduced depression scores but not anxiety scores.

Citation: Yu et al. (2024). Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma. Cellular and Molecular Life Sciences.•DOI: 10.1007/s00018-017-2671-1
Cognitive function & mood
Moderate
Population: Community-dwelling older adults
Study type: RCT
Dose context: — • Duration: 12 weeks

Probiotic supplementation improved cognitive function & mood in older adults.

Citation: Kim et al. (2021). Probiotic Supplementation Improves Cognitive Function and Mood with Changes in Gut Microbiota in Community-Dwelling Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial. Journal of Gerontology.•DOI: 10.1093/gerona/glaa090
Stack pre-check
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Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
No interactions detected
No known absorption conflicts, pharmacokinetic conflicts, or synergies found between the ingredients in this stack.

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