StackTerminal.Health

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@dave.asprey

This is why Vitamin B6 supplements are dangerous for your health! ⚠️

MIXED
TrustworthinessMixed

The claim that high doses of pyridoxine can cause peripheral neuropathy is supported, but the assertion that 10 mg is harmful is overstated. The recommendation to use P5P over pyridoxine lacks strong evidence for most people.

Creator history
See @dave.asprey's full track record — how often their claims check out.
PRO
Detected Supplements (6)
Vitamin B6 (Pyridoxine)"Vitamin B6" in reel
Moderate
10mg mentionedBelow typical range
Vitamin B6 (Pyridoxine)Overstated

10 mg of pyridoxine clogs receptors and is harmful.

There is no strong evidence that 10 mg of pyridoxine is harmful; typical doses for therapeutic effects are higher.

Vitamin B6 (Pyridoxine)Supported

High doses of pyridoxine cause peripheral neuropathy.

High doses of pyridoxine, typically above 100 mg, have been associated with peripheral neuropathy.

Vitamin B6 (Pyridoxine)Misleading

P5P is the only safe form of vitamin B6.

While P5P is an active form of B6, pyridoxine is generally safe at recommended doses for most people.

Vitamin B6 (Pyridoxine)"Vitamin B6" in reel
Moderate
100mg mentionedDose in range
Vitamin B6 (Pyridoxine)Overstated

10 mg of pyridoxine clogs receptors and is harmful.

There is no strong evidence that 10 mg of pyridoxine is harmful; typical doses for therapeutic effects are higher.

Vitamin B6 (Pyridoxine)Supported

High doses of pyridoxine cause peripheral neuropathy.

High doses of pyridoxine, typically above 100 mg, have been associated with peripheral neuropathy.

Vitamin B6 (Pyridoxine)Misleading

P5P is the only safe form of vitamin B6.

While P5P is an active form of B6, pyridoxine is generally safe at recommended doses for most people.

Vitamin B6 (Pyridoxine)"Vitamin B6" in reel
Moderate
500mg mentionedAbove typical range
Vitamin B6 (Pyridoxine)Overstated

10 mg of pyridoxine clogs receptors and is harmful.

There is no strong evidence that 10 mg of pyridoxine is harmful; typical doses for therapeutic effects are higher.

Vitamin B6 (Pyridoxine)Supported

High doses of pyridoxine cause peripheral neuropathy.

High doses of pyridoxine, typically above 100 mg, have been associated with peripheral neuropathy.

Vitamin B6 (Pyridoxine)Misleading

P5P is the only safe form of vitamin B6.

While P5P is an active form of B6, pyridoxine is generally safe at recommended doses for most people.

P5P
IngredientNo evidence data — unverifiable

This ingredient is not in our library. We cannot assess claims about it.

Transcript
Auto-generated from the reel audio.
I recently posted about the dangers of vitamin B6 or pyridoxine, and a lot of people have questions, so this is for you to learn why I'm saying that. There are two forms of vitamin B6. One of them is called P5P, and that is the form that's biologically compatible. When you take the synthetic form that's in almost every supplement, about 95% of it does not get turned into the biological form, and instead it sticks to your vitamin B6 receptors, and then it clogs them up for more than two years. And the amount of B6 that it takes to do that is 10 milligrams. A lot of supplements have 100 milligrams and sometimes 500 milligrams. What happens if you have too much B6 in the form of pyridoxine? Peripheral neuropathy is a condition where you have numbness, tingling, and pain in your feet, your legs, and your arms, and your hands. This is common in diabetes. It's also common in people who start taking high-dose B6 supplements. This is why my recommendation for you is do not take vitamin B6-containing supplements. If they have a very tiny trace amount, it's probably fine. I don't think it's going to be an issue, but most of the time it's many, many milligrams, and it's in every kind of supplement, every kind of sports drink. You're getting overloaded with a synthetic vitamin. I only take B6 or B-complex supplements if they have the P5P or methylated or active form of this. So if you're dealing with weird numbness and tingling and you're taking sports drinks, supplements, or anything else that has higher doses of B6 in it, that's probably why. This is an industry-wide problem, and this is a call to you. If you're a manufacturer of supplements, consider replacing B6 with P5P because it works for everyone. This is very similar to something like folic acid. For a third of people, like me with my genetics, folic acid is actually toxic for you. But methylated folic acid or folate works fine for everyone. So this is about not allowing regulators or big industry interests to use stuff that harms many people and might benefit some people and to instead make the choices, even if they're slightly more expensive, that benefit everyone who needs something like B6. So to sum this up for you, if it says pyridoxine or it says B6 or it says pyridoxine HCl or pyridoxine hydrochloride, those are the wrong forms. The correct form is P5P. Pyridoxal 5-phosphate or P5P, that's the good form, and the bad form is the other one. If it just says B6, it's the bad form. Go through your supplements, figure out how much you're actually taking, especially if your total from everything is more than 10 milligrams, you need to stop. Me, I won't take anything if it has more than maybe half a milligram in it. Even then, I would prefer to have P5P. If this is helpful, share it with a friend. I'm Dave Asprey, the guy who invented biohacking. I've written four or five New York Times bestsellers and eight books on improving energy levels, brain function, and on living forever. If this information is helpful, follow me here.
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This is why Vitamin B6 supplements are dangerous for your health! ⚠️ Share this video with your friends to help them out. 🙏🏼