StackTerminal.Health

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Folic Acid (Folate, B9)

Periconception folic acid lowers neural tube defect risk; standard public-health recommendation is 400 mcg/day for women who could become pregnant.

womens-healthpregnancypreconceptionmetabolic-health
Evidence last reviewed: 04 Apr 2026
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Evidence
2 records
Neural tube defect prevention — landmark RCT
Women with prior NTD-affected pregnancyRandomized controlled trial
PUBMEDHigh

The MRC Vitamin Study found a 72% protective effect of folic acid (4 mg/day) against recurrence of neural tube defects in a landmark double-blind multinational RCT of 1,195 completed pregnancies.

Dose: 4 mgDuration: Periconception period
Neural tube defect prevention
Women capable of becoming pregnantGuideline / public health recommendation
PUBMEDHigh

Daily 400 mcg folic acid is recommended preconception to reduce neural tube defect risk.

Dose: 0 mgDuration: Preconception + early pregnancy
Forms
Tablet
Often 0.4 mg (400 mcg) per tablet

Stacks containing Folic Acid (Folate, B9)

Public community stacks that include this ingredient.

Explore all stacks →
womens-healthfertilitypreconception

This stack addresses the key nutritional & hormonal drivers of female fertility. Folate is essential for DNA synthesis & embryo development. Myo-inositol is the most evidence-backed intervention for improving ovarian function, egg quality, & cycle regularity — particularly in PCOS. CoQ10 restores mitochondrial energy in aging oocytes, & Vitex supports luteal phase adequacy through LH modulation.

Folic Acid (Folate, B9)
0mg
Myo-Inositol
4000mg
Coenzyme Q10
600mg
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