StackTerminal.Health

Folic Acid (Folate, B9)

Periconception folic acid lowers neural tube defect risk; standard public-health recommendation is 400 mcg/day for women who could become pregnant.

womens-healthpregnancypreconceptionmetabolic-health
Dosing model
FLATFixed dose (no body-weight scaling).
Min dose
0 mg
Max dose
0 mg
Rounding
0 mg
Buy this ingredient← Back

Stacks containing Folic Acid (Folate, B9)

Public community stacks that include this ingredient.

Explore all stacks →
No public stacks include this ingredient yet.
Evidence
2 records
Neural tube defect prevention
Women capable of becoming pregnant • Guideline / public health recommendation
High

Daily 400 mcg folic acid is recommended preconception to reduce neural tube defect risk.

Dose: 0 mg • Duration: Preconception + early pregnancy
Citation: CDC – About Folic Acid (recommendation: 400 mcg/day)
Neural tube defect prevention — landmark RCT
Women with prior NTD-affected pregnancy • Randomized controlled trial
High

The MRC Vitamin Study found a 72% protective effect of folic acid (4 mg/day) against recurrence of neural tube defects in a landmark double-blind multinational RCT of 1,195 completed pregnancies.

Dose: 4 mg • Duration: Periconception period
Citation: MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet. 1991;338(8760):131-137.
Forms
Tablet
Often 0.4 mg (400 mcg) per tablet