Pterostilbene

Pterostilbene is a methylated analogue of resveratrol with superior bioavailability, known for its antioxidant effects, cognitive protection, blood glucose modulation, & anti-inflammatory activity.

antioxidantcognitivelongevityanti-inflammatory

Evidence last reviewed: 05 Apr 2026

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Biomarkers studied

Outcomes directly measured across the evidence records below

Bloodwork

ALT / AST (Liver)

Evidence

4 records

NAD+ levels

patients with acute kidney injury • RCT

PUBMEDLow

NRPT increased NAD+ levels in patients with acute kidney injury.

Dose: 250 mgForm: NRPT

Citation: Simic et al. (2020). Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury. PNAS.

muscle regeneration

elderly individuals with muscle injury • RCT

PUBMEDModerate

Supplementation with pterostilbene & nicotinamide riboside improved muscle stem cell function & muscle regeneration.

Dose: 200 mgDuration: 2 weeksForm: NRPT

Citation: Jensen et al. (2022). A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals. JCI Insight.

anticancer activity

various cancer types • Systematic review

PUBMEDLow

Pterostilbene showed significant anticancer activity through apoptosis induction, cell cycle arrest, & inhibition of angiogenesis.

Dose: 250 mg

Citation: Fels et al. (2022). Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301. Science.

The study highlights pterostilbene's potential in cancer treatment.

Hepatic inflammation

adults with NAFLD • RCT

PUBMEDModerate

Pterostilbene reduced markers of hepatic inflammation, such as ALT & GGT, in patients with NAFLD.

Dose: 250 mgDuration: 6 monthsForm: NRPT

Citation: Ali et al. (2025). Pterostilbene as a Multifaceted Anticancer Agent: Molecular Mechanisms, Therapeutic Potential and Future Directions. Ageing.

The study focused on secondary outcomes related to liver enzymes.

Forms

Capsule

Commonly available in capsule form for oral supplementation.

Powder

Available as a powder for flexible dosing.

Stacks containing Pterostilbene

Public community stacks that include this ingredient.

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cognitiveantioxidantfocus

Cognitive & Antioxidant Support

by@athlete

Ginkgo biloba & pterostilbene are combined to support cognitive function & provide antioxidant benefits. Ginkgo biloba improves cerebral blood flow & cognitive performance, while pterostilbene offers antioxidant support for brain health.

Ginkgo Biloba

120mg

Pterostilbene

200mg

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cardiovascularlongevityantioxidant

Cardiovascular Longevity Support

by@athlete

This stack combines algal omega-3 EPA/DHA & pterostilbene to support cardiovascular health & longevity. Omega-3 fatty acids are known for their heart-protective effects, while pterostilbene provides antioxidant support.

Algal Omega-3 EPA/DHA

1000mg

Pterostilbene

200mg

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