StackTerminal.Health

BETA

Passionflower

Passionflower is an anxiolytic herb known for its GABA-A modulating properties, used to alleviate generalized anxiety, insomnia, & symptoms of opioid withdrawal.

anxietysleepstressrelaxation
Evidence last reviewed: 05 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Sleep
Sleep Quality (subjective)
Cognitive
AnxietyPerceived Stress
Evidence
5 records
Anxiety reduction
Adults with anxiety disordersSystematic review
PUBMEDModerate

Passionflower preparations were found to reduce anxiety levels, with effects less evident in mild anxiety.

Dose: 500 mg
Opioid withdrawal symptom reduction
Patients undergoing opioid withdrawalSystematic review
PUBMEDLow

Passionflower may aid in reducing symptoms of opioid withdrawal.

Dose: 500 mg
Stress reduction
Adults with stress-related disordersSystematic review
PUBMEDModerate

Passionflower helps reduce stress & can be helpful in treating insomnia, anxiety, & depression.

Dose: 500 mg
Sleep improvement
Subjects with insomnia disorderSystematic review
PUBMEDLow

Passionflower may benefit the treatment of insomnia, though evidence is limited by small sample sizes.

Dose: 500 mg
Anxiety reduction
Generalized anxiety disorder patientsRCT
PUBMEDModerate

Passionflower extract was comparable to oxazepam in reducing anxiety symptoms.

Dose: 500 mgForm: Extract
Forms
Extract
Commonly used in supplements for anxiety and sleep.
Tea
Traditional form for calming effects.
Capsule
Standardized doses for convenience.

Stacks containing Passionflower

Public community stacks that include this ingredient.

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sleeprelaxationcalm

Combining Tryptophan with Passionflower can enhance sleep quality and promote relaxation. Tryptophan is a precursor to serotonin and melatonin, supporting sleep, while Passionflower is known for its calming effects.

L-Tryptophan
1000mg
Passionflower
500mg
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sleeprelaxationcalm

Valerian root & passionflower are combined to aid sleep & promote relaxation. Valerian root is known for its calming effects, while passionflower helps reduce anxiety & improve sleep quality.

Valerian Root
600mg
Passionflower
500mg
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View