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BETA

L-Tyrosine

L-Tyrosine is an amino acid precursor to dopamine, norepinephrine, & thyroid hormones, often used to support cognitive performance under stress, cold, & sleep deprivation.

cognitivestressfocusperformance

Evidence last reviewed: 05 Apr 2026

Evidence
5 records
5 recordsBest grade:Moderate
Biomarkers
Cognitive FunctionPerceived Stress

Moderate evidence suggests L-Tyrosine can improve cognitive performance in adults under sleep deprivation, stress, and cold conditions. However, more research is needed to fully understand its effects across different populations and contexts.

cognitive performance under sleep deprivation
adults under sleep deprivation · RCT
Moderate

L-Tyrosine supplementation improved cognitive performance in adults experiencing sleep deprivation.

Dose: 2000 mgDuration: single doseForm: CapsuleTiming: before cognitive tasks
Based on known pharmacology & typical dosing.
cognitive performance under cold stress
military personnel in cold environments · RCT
Moderate

L-Tyrosine improved cognitive performance in military personnel exposed to cold stress.

Dose: 2000 mgDuration: single doseForm: TabletTiming: before exposure to cold
Based on known pharmacology & typical dosing.
cognitive performance under stress
healthy school-aged children · RCT
Moderate

L-Tyrosine, in combination with L-theanine, improved markers of stress & cognitive performance during a virtual reality-based active shooter training drill.

Dose: 2000 mg
Working memory under cold exposure
Healthy adults undergoing cold stress · RCT
Moderate

Tyrosine supplementation significantly mitigated cold-induced working memory deficits; proposed mechanism via maintenance of brain catecholamine levels during physiological stress.

Dose: 2000 mgDuration: Acute
Benefits appear specific to conditions of catecholamine depletion (stress, fatigue, cold).
Cognitive performance under stress / demanding conditions
Healthy adults under stress (cold, sleep loss, cognitive load) · Rapid evidence assessment / systematic review
Low

Weak recommendation in favor of tyrosine for cognitive stress — all reviewed studies showed positive effects; benefits most evident under high environmental demands (cold, fatigue, workload), not at rest.

Dose: 2000 mgDuration: Acute
Tyrosine appears ineffective when catecholamine systems are not stressed; benefits are situational.
Stacks containing L-Tyrosine
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Targets acute performance via nitric oxide support, buffering capacity, & central drive.

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8000mg
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3200mg
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focus

Supports focus & mental clarity without stimulants.

L-Theanine
200mg
L-Tyrosine
1000mg
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stresscognitivefocus

Combining L-Tyrosine with Eleuthero can reduce stress and support cognitive function. L-Tyrosine is known for its role in stress reduction and cognitive enhancement, while Eleuthero is an adaptogen that supports focus and endurance.

L-Tyrosine
500mg
Eleuthero (Siberian Ginseng)
400mg
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sleepfocus

Supports attention & cognitive resilience without stimulants.

L-Theanine
200mg
L-Tyrosine
1000mg
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Community Insights
Forms & usage
How to take it

Take 500-2000 mg daily, ideally before stressful situations or cold exposure.

Capsule
Commonly used for ease of dosing.
Powder
Allows for flexible dosing and mixing with liquids.
Tablet
Convenient for on-the-go use.
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