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Lemon Balm

Lemon Balm is a mild anxiolytic herb that may help reduce anxiety & improve sleep quality, particularly in individuals with mild anxiety or stress-related symptoms.

anxietysleepcognitivestress

Evidence last reviewed: 05 Apr 2026

Evidence
3 records
3 recordsBest grade:High
Biomarkers
Anxiety

The evidence suggests that Lemon Balm can significantly reduce anxiety and depression symptoms, particularly in specific populations like those with diabetes or undergoing hemodialysis. While the results are promising, more research is needed to fully understand its effects across diverse groups.

Anxiety reduction
Hemodialysis patients · RCT
Moderate

Melissa officinalis L. essential oil inhalation reduced anxiety & symptom burden in hemodialysis patients.

Dose: 600 mgDuration: 1 monthForm: Essential OilTiming: During hemodialysis sessions
Anxiety & depression reduction
Type 2 diabetes patients with depression · RCT
Moderate

Significant decrease in depression & anxiety severity in the intervention group compared to baseline.

Dose: 700 mgDuration: 12 weeksForm: Hydroalcoholic Extract
Anxiety reduction
Patients with symptoms of depression or anxiety · Meta-analysis
High
Stacks containing Lemon Balm
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sleepstresscalm

Combining GABA with Lemon Balm can enhance sleep quality and reduce stress. GABA is known for its calming effects, while Lemon Balm supports relaxation and stress reduction.

GABA
500mg
Lemon Balm
600mg
New
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stressmoodcalm

Ashwagandha & lemon balm are combined to support stress reduction & enhance mood. Ashwagandha is an adaptogen that reduces stress & anxiety, while lemon balm provides calming effects & improves mood.

Ashwagandha
300mg
Lemon Balm
600mg
New
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moodanxietystress

5-HTP & lemon balm are combined to support mood & reduce anxiety. 5-HTP is a precursor to serotonin, a neurotransmitter that regulates mood, while lemon balm has calming effects that can help reduce stress & anxiety.

5-HTP
100mg
Lemon Balm
600mg
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Community Insights
Forms & usage
How to take it

Take 300-600 mg of Lemon Balm extract, 30 minutes before bedtime or as needed for anxiety.

Leaf Extract
Commonly used in supplements for anxiety and sleep.
Essential Oil
Used in aromatherapy for anxiety relief.
Hydroalcoholic Extract
Used in clinical trials for anxiety and depression.
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