Krill Oil

Krill oil is a marine oil supplement derived from Antarctic krill, known for its high bioavailability of omega-3 fatty acids, which may support cardiovascular health, reduce inflammation, and alleviate symptoms of PMS.

cardiovascularanti inflammatorycognitivejoint healthmood

Evidence last reviewed: 20 Apr 2026

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Evidence

4 records

4 recordsBest grade:High

Biomarkers

Triglycerides

The evidence suggests krill oil is effective for cardiovascular health and may lower triglyceride levels. However, its impact on knee pain is not significant, indicating variability in effectiveness across different conditions.

Knee pain reduction

Adults with knee osteoarthritis · RCT

Moderate

Krill oil did not significantly improve knee pain compared to placebo.

Dose: 2000 mgDuration: 24 weeks

Citation: Zhang et al. (2025). Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.

Triglyceride levels

Patients with severe hypertriglyceridemia · RCT

Moderate

Krill oil supplementation showed potential in reducing triglyceride levels.

Dose: 1000 mg

Citation: Hill et al. (2023). A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis.

Omega-3 index

Well-conditioned power training athletes · RCT

Moderate

Krill oil increased the HS-Omega-3 Index and plasma choline levels.

Dose: 1000 mg

Citation: Drobnic et al. (2021). Krill-Oil-Dependent Increases in HS-Omega-3 Index, Plasma Choline and Antioxidant Capacity in Well-Conditioned Power Training Athletes.

Cardiovascular health

General human population · Systematic review and meta-analysis

High

Krill oil supplementation may support cardiovascular health.

Dose: 1000 mg

Citation: Huang et al. (2023). Clinical effectiveness of krill oil supplementation on cardiovascular health in humans: An updated systematic review and meta-analysis of randomized controlled trials.

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Cardiovascular Health and Antioxidant Support

by@athlete

Combining Krill Oil with Vitamin E can support cardiovascular health and provide antioxidant protection. Krill Oil is known for its omega-3 fatty acids, supporting heart health, while Vitamin E provides antioxidant support and reduces oxidative stress.

Krill Oil

1000mg

Vitamin E (Tocopherols)

50mg

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Forms & usage▾

How to take it

Take 1-2 grams daily with meals for optimal absorption.

Softgel

Common form for oral supplementation, often containing astaxanthin.

Liquid

Less common, used for those who prefer not to take capsules.

My notes▾