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Evening Primrose Oil

GLA-rich oil with evidence for PMS, breast pain, & menopausal symptoms.

womens healthinflammationhormones

Evidence last reviewed: 04 Apr 2026

Evidence
1 record
1 recordBest grade:Moderate

The evidence for Evening Primrose Oil shows moderate benefits for cyclical breast pain and some reduction in menopausal symptoms, but results for PMS mood improvement are inconsistent. The quality of studies varies, indicating a need for more robust research.

PMS / cyclical mastalgia / menopausal symptoms
Women with PMS; perimenopausal women · RCTs (mixed quality)
Moderate

Consistent benefit for cyclical breast pain; mixed results for PMS mood; some menopausal hot flush reduction.

Dose: 1500 mgDuration: 3–6 months
May take 3+ months for full effect.
Stacks containing Evening Primrose Oil
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hormonalwomens-healthbalance

Combining Shatavari with Evening Primrose Oil can support hormonal balance in women. Shatavari is an adaptogen that supports reproductive health, while Evening Primrose Oil provides essential fatty acids for hormonal balance.

Shatavari
500mg
Evening Primrose Oil
1000mg
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womens-healthconstraints

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Built from your selected goals, constraints, diet, & the supplement evidence library. You can edit doses & timing.

Vitamin B-Complex
26mg
Vitamin C
500mg
Ashwagandha
600mg
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Forms & usage
How to take it

Take 500-1000 mg daily, preferably with meals.

Evening primrose oil softgel (8–10% GLA)
Dose by GLA content.
Safety & trade-offs2
Neural

May lower seizure threshold — avoid with epilepsy medications or phenothiazines

Interaction

Mild blood-thinning activity — caution with anticoagulants

High  Moderate   Low / note

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