Calcium D-Glucarate
Calcium D-Glucarate is a supplement that may aid in detoxification & hormonal balance by inhibiting beta-glucuronidase, potentially supporting estrogen detoxification & cancer prevention.
Evidence last reviewed: 05 Apr 2026
- •pregnant or breastfeeding individuals
- •those with kidney issues
- •people on certain medications
The evidence for Calcium D-Glucarate is largely theoretical and categorized as very low strength. While it may aid in detoxification and hormonal balance, significant gaps in research and direct evidence limit its reliability.
Cancer preventionGeneral population · TheoreticalVery low
Potential role in cancer prevention through detoxification pathways, though direct evidence is lacking.
Liver healthGeneral population · TheoreticalVery low
May support liver health by aiding in the detoxification process.
Estrogen detoxificationGeneral population · TheoreticalVery low
Calcium D-Glucarate may support estrogen detoxification by inhibiting beta-glucuronidase, reducing the reabsorption of estrogen.
Liver Detox & Protection
Milk thistle & calcium d-glucarate are combined to support liver detoxification & protection. Milk thistle is known for its hepatoprotective properties, while calcium d-glucarate aids in detoxification processes.
Forms & usage▾
Take 500-1500 mg daily, preferably with meals.