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Enhanced Cognitive Performance

Combining DMAE with Uridine Monophosphate can enhance cognitive function and focus. DMAE is known for its role in improving attention and mental clarity, while Uridine supports neuroplasticity and cognitive enhancement.

What this is for
General support
cognitive, focus, nootropic
Why you are seeing this
Goal fit: cognitive, focus, nootropic.
What to do next
Add body metrics if you want dose previews to reflect your weight rather than the reference dose.
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Public•Built 20 Apr 2026•2 ingredients•No interactions detected
Core stack
The main ingredients doing the work.
2 key items
DMAE (Dimethylaminoethanol)Moderate
Morning •
DMAE enhances attention and mental clarity.
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350mg
skin firming
Moderate
Population: general population with aging skin
Study type: RCT
Dose context: 350 mg typical • Duration: 16 weeks

3% DMAE facial gel applied daily improved skin firmness.

Citation: Grossman et al. (2005). The role of dimethylaminoethanol in cosmetic dermatology. Journal.•DOI: 10.2165/00128071-200506010-00005
cognitive function
Moderate
Population: subjects with threshold emotional disturbance
Study type: RCT
Dose context: 350 mg typical • Duration: 12 weeks

DMAE-containing supplement reduced theta and alpha1 power in EEG, indicating potential cognitive benefits.

Citation: Dimpfel et al. (2003). Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional states. Journal.•DOI: 10.1034/j.1600-0846.2002.10295.x
skin tensile effect
Moderate
Population: general population
Study type: RCT
Dose context: 350 mg typical

DMAE gel showed a significant cutaneous tensile effect compared to placebo.

Citation: Uhoda et al. (2002). Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel. Journal.•DOI: 10.1034/j.1600-0846.2002.10295.x
Uridine MonophosphateLow
Morning •
Uridine supports neuroplasticity and cognitive enhancement.
Buy ingredient →
500mg
Cognitive function
Low
Population: Patients with Alzheimer's disease
Study type: Systematic review
Dose context: 500 mg typical

Preliminary evidence suggests that uridine monophosphate, as part of a multinutrient combination, may support cognitive function in Alzheimer's disease.

Citation: Engelborghs et al. (2014). Rationale and clinical data supporting nutritional intervention in Alzheimer's disease. Journal.•DOI: 10.1179/0001551213Z.0000000006
Part of a multinutrient intervention.
Pain reduction
Low
Population: Patients with peripheral entrapment neuropathy
Study type: Cohort
Dose context: 500 mg typical • Duration: 2 months

Uridine monophosphate, combined with folic acid and vitamin B12, reduced pain scores in patients with peripheral entrapment neuropathy.

Citation: Negrão et al. (2016). Uridine monophosphate, folic acid and vitamin B12 in patients with symptomatic peripheral entrapment neuropathies. Journal.•DOI: 10.2217/pmt.15.60
Neuroprotection
Low
Population: Patients with Alzheimer's disease
Study type: Systematic review
Dose context: 500 mg typical

Uridine monophosphate, as part of a multinutrient formula, may contribute to neuroprotection in Alzheimer's disease.

Citation: Rijpma et al. (2015). Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease. Journal.•DOI: 10.1186/s13195-015-0134-1
Part of a multinutrient intervention.
Stack pre-check
No personal data connected — connect wearables or upload bloodwork for a personalised check
Clean
Supplements
2
Training load
Unknown
No flags
No duplication, stimulant, interaction, or recovery concerns detected.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
DMAE (Dimethylaminoethanol)
Take ~2h before the intended effect window
Reaches peak plasma concentration in ~2h. Half-life ~3h.
Uridine Monophosphate
Take ~2h before the intended effect window
Reaches peak plasma concentration in ~2h. Half-life ~3h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

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