Stress & Adaptogen Support

B84· Mostly solid

Public • 06 Apr 2026

Holy basil & eleuthero are combined to support stress reduction & adaptogenic benefits. Holy basil is known for its calming effects, while eleuthero enhances the body's resilience to stress.

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Stress & Adaptogen Support

stress adaptogen calm

Holy Basil (Tulsi)

Daily with food

MODERATE

300mg

Eleuthero (Siberian Ginseng)

Daily with food

MODERATE

400mg

No interactions detected

Each dose includes evidence rationale · doses personalized to your weight

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No duplication, stimulant, interaction, or recovery concerns detected.

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Interaction Analysis

Pharmacokinetic + pair-level checks

Timing optimizations

Eleuthero (Siberian Ginseng)

Take ~1h before the intended effect window

Reaches peak plasma concentration in ~1h. Half-life ~3h.

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

Supplements

2 items

Holy Basil (Tulsi)Moderate

Daily with food •

Provides calming effects to reduce stress.

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300mg

immune-function

Moderate

Population: healthy volunteers

Study type: RCT

Dose context: 300 mg typical (range: 300–300 mg)

Tulsi leaves extract demonstrated immunomodulatory effects.

Citation: Devpura et al. (2021). Randomized placebo-controlled pilot clinical trial on the efficacy of ayurvedic treatment regime on COVID-19 positive patients.•DOI: 10.1016/j.phymed.2021.153494

cognitive-function

Low

Population: general population

Study type: Systematic review

Dose context: 600 mg typical

Tulsi is noted for its potential neuroprotective & cognitive-enhancing effects.

Citation: Kushwah et al. (2023). Herbal Therapeutics for Alzheimer's Disease: Ancient Indian Medicine System from the Modern Viewpoint.•DOI: 10.2174/1570159X21666230216094353

Discusses potential benefits in Alzheimer's disease.

immune-function

Moderate

Population: healthy volunteers

Study type: RCT

Dose context: 300 mg typical (range: 300–300 mg) • Duration: 4 weeks

Tulsi extract significantly increased levels of IFN-γ, IL-4, T-helper cells, & NK-cells.

Citation: Megalaa et al. (2018). A comparative evaluation of the anticaries efficacy of herbal extracts (Tulsi and Black myrobalans) and sodium fluoride as mouthrinses in children: A randomized controlled trial.•DOI: 10.4103/ijdr.ijdr_790_16

Eleuthero (Siberian Ginseng)Moderate

Daily with food •

Enhances the body's resilience to stress.

Buy ingredient →

400mg

fatigue reduction

Moderate

Population: patients with chronic fatigue

Study type: RCT

Dose context: 400 mg typical • Duration: 2 months

Siberian ginseng showed potential efficacy in reducing fatigue in patients with moderate fatigue.

Citation: Hartz et al. (2004). Randomized controlled trial of Siberian ginseng for chronic fatigue. Phytomedicine.•DOI: 10.1016/S0944-7113(11)80025-5

Effectiveness was more pronounced in patients with less severe fatigue.

quality of life improvement

Moderate

Population: elderly individuals

Study type: RCT

Dose context: 400 mg typical

Eleuthero improved quality of life in elderly individuals.

Citation: Cicero et al. (2004). Effects of Siberian ginseng (Eleutherococcus senticosus maxim.) on elderly quality of life: a randomized clinical trial.•DOI: 10.1016/j.archger.2004.04.012

stress adaptation

Moderate

Population: general population

Study type: Systematic review

Dose context: 400 mg typical

Eleuthero is recognized as a natural adaptogen that enhances the body's stability against physical stress.

Citation: Todorova et al. (2021). Plant Adaptogens-History and Future Perspectives. Nutrients.•DOI: 10.3390/nu13082861

Highlights the historical & potential future applications of plant adaptogens.

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