StackTerminal.Health

BETA
Alternative layoutGrade B · 76Mostly solid

Your personalized stack

Built from your goals & the supplement evidence library. You can edit doses & timing.

What this is for
General support
strength, recovery, daily
Why you are seeing this
Goal fit: strength, recovery, daily.
What to do next
Keep the core idea, then tighten timing or overlap issues to make the stack easier to run.
PublicBuilt 14 Mar 20263 ingredientsNo interactions detected
Core stack
The main ingredients doing the work.
3 key items
Morning or pre-workout • Caffeine anhydrous
Caffeine acutely improves multiple performance outcomes; common effective range is ~3–6 mg/kg in many studies, with high inter-individual variability.
200mg
Trade-offs & context
Sleep

Impairs sleep onset and deep sleep if consumed within 8–10 hours of bedtime

Tolerance

Tolerance develops within 1–2 weeks of daily use, reducing efficacy

Neural

Withdrawal: headache and fatigue on cessation after sustained daily use

Cardiovascular

Elevated heart rate, anxiety, jitteriness — individual sensitivity varies widely

Context: doses >400mg

Endurance & sport performance
High
Population: Athletes and active adults
Study type: ISSN Position Stand (systematic review)
Dose context: 200 mg typical (range: 100–400 mg) • Duration: Acute (single dose)

Strong evidence that 3–6 mg/kg caffeine improves endurance, strength, & power; benefits consistent but moderated by genetics & habituation.

Citation: Guest NS et al. J Int Soc Sports Nutr. 2021;18(1):1.DOI: 10.1186/s12970-020-00383-4https://pubmed.ncbi.nlm.nih.gov/33388079/
CYP1A2 & ADORA2A genotypes influence individual response.
Cognitive performance (attention, reaction time)
High
Population: Healthy adults (31 trials, n=1,455)
Study type: Systematic review & meta-analysis
Dose context: 200 mg typical (range: 100–400 mg) • Duration: Acute

Caffeine significantly improves reaction time (g=0.28) & accuracy (g=0.27) on attention tasks; dose ≥200 mg shows larger effects.

Citation: Grgic J et al. Int J Sport Nutr Exerc Metab. 2021;31(3):199–206.https://pubmed.ncbi.nlm.nih.gov/33800853/
Benefits are acute; tolerance develops with daily use.
Sleep disruption (safety warning)
High
Population: Healthy adults
Study type: Systematic review & meta-analysis
Dose context: 200 mg typical (range: 100–400 mg) • Duration: Acute

Caffeine prolongs sleep latency, reduces total sleep time & efficiency; clinically meaningful disruption occurs with 400 mg within 8–12 h of bedtime.

Citation: Gardiner C et al. Sleep Med Rev. 2023;68:101764.DOI: 10.1016/j.smrv.2022.101764https://pubmed.ncbi.nlm.nih.gov/36870101/
Avoid caffeine within 6–8 h of intended sleep time when sleep is a priority.
Beta-AlanineModerate
Daily (any time) • Beta-alanine
Chronic beta-alanine supplementation increases muscle carnosine & can improve performance, commonly using multi-gram daily dosing over weeks.
3200mg
Exercise capacity & performance (broader meta-analysis)
Moderate
Population: Mixed athletes; 1,461 participants across 40 studies
Study type: Systematic review & meta-analysis
Dose context: 4800 mg typical (range: 3200–6400 mg) • Duration: 4–12 weeks

Significant overall effect size (ES = 0.18, 95% CI 0.08–0.28); greatest benefit for exercise in 1–10 min duration window.

Citation: Saunders B et al. Br J Sports Med. 2017;51(8):658–669.DOI: 10.1136/bjsports-2016-096396https://pubmed.ncbi.nlm.nih.gov/27797728/
Effect size modest; larger in capacity vs. performance measures.
High-intensity exercise performance (1–4 min efforts) via muscle carnosine elevation
High
Population: Athletes and trained adults
Study type: ISSN Position Stand (systematic review)
Dose context: 4800 mg typical (range: 3200–6400 mg) • Duration: 4–12 weeks

4–6 g/day for ≥4 weeks significantly augments muscle carnosine (intracellular pH buffer) & improves exercise lasting 1–4 min; no benefit for efforts <60 s.

Citation: Trexler ET et al. J Int Soc Sports Nutr. 2015;12:30.DOI: 10.1186/s12970-015-0090-yhttps://pubmed.ncbi.nlm.nih.gov/26175657/
Paresthesia (tingling) is common but harmless; split dosing reduces it.
Vitamin D3Moderate
With food • Cholecalciferol
Effectively raises serum 25(OH)D concentrations.
50mg
Fracture prevention in elderly adults
Moderate
Population: Ambulatory and institutionalized elderly persons
Study type: Systematic review and meta-analysis of RCTs
Dose context:

Vitamin D at 700–800 IU/day reduced hip fracture risk by 26% (RR 0.74) & any nonvertebral fracture by 23% (RR 0.77); no significant benefit was observed at 400 IU/day.

Citation: Bischoff-Ferrari HA, Willett WC, Wong JB, et al. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA. 2005;293(18):2257-64.DOI: 10.1001/jama.293.18.2257https://pubmed.ncbi.nlm.nih.gov/15886381/
Dose-dependent effect; 400 IU/day insufficient for fracture prevention.
Prevention of acute respiratory tract infections
Moderate
Population: Children and adults (ages 0–95); 25 RCTs, n=11,321
Study type: Systematic review and meta-analysis of individual participant data from RCTs
Dose context:

Vitamin D supplementation reduced risk of acute respiratory tract infection (adjusted OR 0.88, 95% CI 0.81–0.96); greatest benefit in those with baseline deficiency (<25 nmol/L) & those receiving daily or weekly dosing rather than bolus doses.

Citation: Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583.DOI: 10.1136/bmj.i6583https://pubmed.ncbi.nlm.nih.gov/28202713/
IPD meta-analysis; high statistical power; effect strongest in vitamin D-deficient individuals.
Vitamin D status & physical performance in athletes
Low
Population: Competitive and recreational athletes
Study type: Narrative review
Dose context:

Vitamin D insufficiency is prevalent among athletes, particularly indoor athletes & those in northern latitudes in winter. Insufficiency is associated with reduced muscle strength, power, & endurance; supplementation of 2,000–6,000 IU/day recommended to maintain 25(OH)D >40 ng/mL.

Citation: Yoon S, Kwon O, Kim J. Vitamin D in athletes: focus on physical performance and musculoskeletal injuries. Phys Act Nutr. 2021;25(2):20-25.DOI: 10.20463/pan.2021.0011https://pubmed.ncbi.nlm.nih.gov/34315203/
Narrative review; prevalence data robust, intervention evidence more limited.
Stack pre-check
No personal data connected — connect wearables or upload bloodwork for a personalised check
1 caution
Supplements
3
Training load
Unknown
Caffeine (est.)
200 mg
Caution
Moderate stimulant load (~200 mg caffeine)
Estimated 200 mg/day of caffeine from explicit items in this stack. Works well for most people, but monitor sleep quality — especially if you're also consuming coffee or tea throughout the day.
Note
Stimulants without sleep-support counterbalance
This stack has a notable stimulant load but no sleep-support ingredient. If sleep quality is important to you, consider adding magnesium, L-theanine, or glycine in the evening to offset stimulant effects.

Pre-check is rule-based, not medical advice. Consult a healthcare professional for personalised guidance.

Interaction Analysis
Pharmacokinetic + pair-level checks
Timing optimizations
Caffeine
Before 2pm
Half-life ~5h. A 2pm dose may still be at 50% plasma at 7pm, disrupting sleep architecture. (Onset: ~45 min, half-life: ~5h)
Beta-Alanine
Pre-workout (split doses)
Paresthesia (tingling) is dose-dependent — split into 1–1.6g doses. Works acutely to sustain carnosine levels pre-exercise. (Onset: ~30 min, half-life: ~2.5h)
Vitamin D3
With largest fat-containing meal
Fat-soluble. Co-ingestion with dietary fat increases absorption by 32–56%. (Onset: ~12h, half-life: ~360h)

Interaction analysis is based on peer-reviewed pharmacology. PMID links go to PubMed. Not medical advice.

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