I've been megadosing 10 to 15 grams of glycine every day for two years. I think glycine is one of the safest and most effective health supplements that you could take. It supports collagen turnover for smooth and soft skin. It supports glutathione synthesis for your body's antioxidant system. It reduces visceral fat around the organs. It lowers blood sugar and protects your skin against glycation. And it improves sleep and reduces mental anxiety. Here are the biggest things I noticed from taking large amounts of glycine. I've seen my visceral fat decrease from 350 grams to 54 grams. My skin health has improved, specifically some fine lines on my forehead that I had five years ago, which are now completely gone. My sleep quality and speed of falling asleep are much better, and I'm clocking in 100 sleep scores on a regular basis, whereas it used to be much worse. And my blood sugar levels are optimal, despite me eating over 300 grams of carbs every day. Now, glycine is generally very safe, and I've never had any negative symptoms from taking large amounts of glycine. I personally have taken up to 30 grams of glycine per day, and there are studies where they even give people 90 grams of glycine without side effects.