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I am thrilled today to be able to talk about one of my favorite topics, which is mitochondria, longevity, energy, how we make energy in our bodies, how we deal with the ravages of aging, which at 65 now, I am very interested in. And again, I'm really lucky to have this brilliant Harvard-educated physician, inventor, biomedical entrepreneur with more than 30 years of experience in drug discovery, development, is a guy named Dr. Salzman, who's published over 170 papers, been cited in 12,000 peer-reviewed papers, had 60 patents, and he even figured out a way to look at DNA repair around breast cancer and ovarian cancer, which is amazing. He's just an incredible guy. And he also worked a lot in the areas of the gut microbiome, inflammation, mitochondrial dysfunction, and he's also working with a company called Wonderfeel. And I just want to have him on because I think this is a real important conversation to understand how their systems work, how their bodies work. I always want people to have the owner's manual for their body. So I'm very, very enthusiastic about having people do that. I'm going to accept the Wonderfeel.
But let's get Dr. Salzman on.
And then we'll have this chat about NAD and NMN and NR, probably stuff you've heard about. It's kind of a hot supplement when it comes to the aging world.
Hey, there you are. Dr. Salzman, how are you?
Good morning.
Good to see you.
Good to see you.
Where are you? Are you in Israel?
No, I'm actually outside of San Francisco in this gorgeous Sonoma Valley.
Oh, so that's not a fake background?
No, no, it's the real rain, the redwood and everything. It's all real here.
Amazing, amazing. Wow, so glad to have you. It's good to talk to you again, good to see you again. I just sort of gave a little introduction of you. And I think what I'd love to do is sort of dive into the work you've done over the last years around NAD, NMN, NR, which are all kind of different acronyms for molecules that our body uses and makes to create energy and do many, many other things to activate DNA repair. So what are these things? What is NAD? People have heard about it. What is NMN? What is NR? What are they?
Well, these are the centerpiece of our metabolism, our energy, our DNA repair. They're safeguarding our genome. I mean, these are probably the most central molecules involved in our health. And of course, with aging, they change in their levels and their activity. So the conversation today is very worthy. We're talking about something that is about the most important molecule in our body dictating how we do.
So basically this kind of runs the show when it comes to energy, DNA repair, oxidative stress, inflammation. I actually heard David Sinclair saying giving NMN to mice
Caption
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