StackTerminal.Health

BETA

Sulforaphane

Sulforaphane is an isothiocyanate derived from broccoli sprouts that activates the Nrf2 pathway, promoting antioxidant & detoxification processes. It shows potential benefits for cancer prevention, autism spectrum disorder, & cardiovascular protection.

antioxidantanti-inflammatorydetoxificationanti-cancer
Evidence last reviewed: 05 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Metabolic
Insulin SensitivityBlood Glucose
Cognitive
Cognitive FunctionMood / Wellbeing
Inflammation
Oxidative Stress (MDA)
Immune
Immune Function
Evidence
3 records
Insulin resistance
Individuals with insulin resistance • RCT
PUBMEDModerate

Sulforaphane improved insulin resistance by activating specific gut microbiota pathways.

Dose: 30 mgDuration: 15 weeksForm: Broccoli Sprout Extract
Citation: Tian et al. (2024). Improving insulin resistance by sulforaphane via activating the Bacteroides and Lactobacillus SCFAs-GPR-GLP1 signal axis.
The study demonstrated mechanistic insights into sulforaphane's effects on insulin resistance.
Cancer prevention
Former smokers at high risk for lung cancer • RCT
PUBMEDModerate

Sulforaphane led to small changes in primary outcome measures, with significant improvements in secondary measures.

Dose: 30 mgDuration: Phase II trialForm: Broccoli Sprout Extract
Citation: Yuan et al. (2025). Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer.
The study highlighted sulforaphane's safety & effectiveness in secondary measures.
Autism Spectrum Disorder symptoms
Children with Autism Spectrum Disorder • RCT
PUBMEDModerate

Sulforaphane showed a trend towards improvement in autism symptoms, with significant improvements in caregiver ratings on secondary outcome measures.

Dose: 30 mgDuration: 15 weeksForm: Broccoli Sprout Extract
Citation: Tian et al. (2024). Improving insulin resistance by sulforaphane via activating the Bacteroides and Lactobacillus SCFAs-GPR-GLP1 signal axis.
The study noted non-statistically significant trends but significant improvements in secondary measures.
Forms
Broccoli Sprout Extract
Commonly used for its high sulforaphane content.
Capsule
Standardized doses for supplementation.

Stacks containing Sulforaphane

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liver-healthantioxidantdetoxification

Liver Health and Antioxidant Support

by@athlete

Combining Schisandra with Sulforaphane can support liver health and provide antioxidant protection. Schisandra is an adaptogen that supports liver function, while Sulforaphane is known for its detoxification and antioxidant properties.

Schisandra (Schisandra chinensis)
1000mg
Sulforaphane
30mg
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