StackTerminal.Health

BETA

Pycnogenol (French Maritime Pine Bark)

Pycnogenol is a standardized pine bark extract rich in procyanidins, known for improving endothelial function, reducing symptoms of chronic venous insufficiency, decreasing osteoarthritis pain, and enhancing attention in ADHD. It has anti-inflammatory, antioxidant, and vascular benefits.

cardiovascularantioxidantjoint-healthanti-inflammatorycognitive
Evidence last reviewed: 20 Apr 2026
Supplement note
Private note on this supplement

Save how you reacted, what dose worked, what to watch for, or anything you want to remember later in your Notes tab.

Sign in to keep a private note on Pycnogenol (French Maritime Pine Bark).
Biomarkers studied
Outcomes directly measured across the evidence records below
Cardiovascular
Blood Pressure
Cognitive
Focus / Attention
Inflammation
IL-6CRP (Inflammation)
Immune
Immune Function
Evidence
5 records
Inflammatory biomarkers reduction
Adults with gingival inflammationRCT
PUBMEDModerate

Pycnogenol supplementation reduced inflammatory biomarkers in saliva and serum.

Dose: 200 mgDuration: 3 months
Skin health improvement
Women with melasmaRCT
PUBMEDLow

Pycnogenol showed efficacy in improving skin health and reducing hyperpigmentation.

Dose: 100 mgDuration: 30 days
Endothelial function improvement
Patients with stable coronary artery diseaseRCT
PUBMEDModerate

Pycnogenol supplementation improved endothelium-dependent vasodilation.

Dose: 150 mgDuration: 10 days
Cognitive function improvement
Adults with ADHDRCT
PUBMEDLow

Pycnogenol was compared to methylphenidate and showed potential benefits in improving attention.

Dose: 100 mg
Post-COVID-19 condition symptom relief
Individuals with post-COVID-19 conditionRCT
PUBMEDModerate

Pycnogenol may alleviate symptoms associated with post-COVID-19 condition.

Dose: 200 mgDuration: 12 weeks
Forms
Capsule
Commonly used form for oral supplementation.
Tablet
Another popular form for ease of use.
Powder
Can be mixed with liquids for those who prefer not to take pills.

Stacks containing Pycnogenol (French Maritime Pine Bark)

Public community stacks that include this ingredient.

Explore all stacks →
cardiovascularantioxidantlongevity

Combining Grape Seed Extract with Pycnogenol can support cardiovascular health and provide antioxidant protection. Grape Seed Extract improves blood flow and reduces oxidative stress, while Pycnogenol supports vascular health and reduces inflammation.

Grape Seed Extract (OPCs)
200mg
Pycnogenol (French Maritime Pine Bark)
100mg
New
View