Modafinil
Modafinil is a wakefulness-promoting agent approved for narcolepsy & shift work disorder, & is widely used off-label as a cognitive enhancer with evidence for improving attention, working memory, & decision-making.
focuscognitiveenergywakefulness
Evidence last reviewed: 05 Apr 2026
Biomarkers studied
Outcomes directly measured across the evidence records below
Cognitive
Cognitive FunctionFocus / Attention
Evidence
3 records
Cognitive enhancement
Adults with treatment-resistant depression • Systematic review
PUBMEDModerate
Modafinil showed significant efficacy in cognitive enhancement compared to placebo.
Dose: 200 mg
Wakefulness
Adults with narcolepsy • Systematic review
PUBMEDHigh
Modafinil is effective in promoting wakefulness in patients with narcolepsy.
Dose: 200 mg
Treatment of stimulant use disorder
Adults with amphetamine-type stimulant use disorder • Systematic review and meta-analysis
PUBMEDModerate
Modafinil showed efficacy in the treatment of amphetamine-type stimulant use disorder.
Dose: 200 mg
Forms
Tablet
Commonly available in 100 mg and 200 mg doses.
Stacks containing Modafinil
Public community stacks that include this ingredient.
cognitiveenergyfocus
Cognitive & Energy Enhancement
by@athlete
Modafinil & methylene blue are combined to enhance cognitive function & energy levels. Modafinil is a wakefulness-promoting agent that improves focus, while methylene blue supports mitochondrial function & cognitive performance.
Modafinil
100mg
Methylene Blue
2mg
New