StackTerminal.Health

BETA

Lemon Balm

Lemon Balm is a mild anxiolytic herb that may help reduce anxiety & improve sleep quality, particularly in individuals with mild anxiety or stress-related symptoms.

anxietysleepcognitivestress
Evidence last reviewed: 05 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Cognitive
Anxiety
Evidence
3 records
Anxiety reduction
Hemodialysis patients • RCT
PUBMEDModerate

Melissa officinalis L. essential oil inhalation reduced anxiety & symptom burden in hemodialysis patients.

Dose: 600 mgDuration: 1 monthForm: Essential OilTiming: During hemodialysis sessions
Citation: Pasyar et al. (2025). The effectiveness of Melissa officinalis L. essential oil inhalation on anxiety and symptom burden of hemodialysis patients: a randomized trial study. Journal.
Anxiety & depression reduction
Type 2 diabetes patients with depression • RCT
PUBMEDModerate

Significant decrease in depression & anxiety severity in the intervention group compared to baseline.

Dose: 700 mgDuration: 12 weeksForm: Hydroalcoholic Extract
Citation: Iwahashi et al. (2025). Lemon Balm (Melissa officinalis L.) Leaf Extract Promotes Endo180 Production in Dermal Fibroblasts and has Antiwrinkle Effect on Human Skin. Journal.
Anxiety reduction
Patients with symptoms of depression or anxiety • Meta-analysis
PUBMEDHigh

Lemon balm significantly improved mean anxiety & depression scores compared with placebo.

Dose: 600 mg
Citation: Ghazizadeh et al. (2021). The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis. Journal.
Forms
Leaf Extract
Commonly used in supplements for anxiety and sleep.
Essential Oil
Used in aromatherapy for anxiety relief.
Hydroalcoholic Extract
Used in clinical trials for anxiety and depression.

Stacks containing Lemon Balm

Public community stacks that include this ingredient.

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stressmoodcalm

Stress & Mood Enhancement

by@athlete

Ashwagandha & lemon balm are combined to support stress reduction & enhance mood. Ashwagandha is an adaptogen that reduces stress & anxiety, while lemon balm provides calming effects & improves mood.

Ashwagandha
300mg
Lemon Balm
600mg
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moodanxietystress

Mood & Anxiety Support

by@athlete

5-HTP & lemon balm are combined to support mood & reduce anxiety. 5-HTP is a precursor to serotonin, a neurotransmitter that regulates mood, while lemon balm has calming effects that can help reduce stress & anxiety.

5-HTP
100mg
Lemon Balm
600mg
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