Evening Primrose Oil
GLA-rich oil with evidence for PMS, breast pain, & menopausal symptoms.
womens-healthinflammationhormones
Evidence last reviewed: 04 Apr 2026
Trade-offs & context
Known concerns, timing considerations, & interactions
Neural
May lower seizure threshold — avoid with epilepsy medications or phenothiazines
Interaction
Mild blood-thinning activity — caution with anticoagulants
Dot colour: ●High concern ●Moderate ● Low / note
Evidence
1 record
PMS / cyclical mastalgia / menopausal symptoms
Women with PMS; perimenopausal women • RCTs (mixed quality)
PUBMEDModerate
Consistent benefit for cyclical breast pain; mixed results for PMS mood; some menopausal hot flush reduction.
Dose: 1500 mgDuration: 3–6 months
Citation: Blommers et al. 2002; Pruthi et al. 2010
May take 3+ months for full effect.
Forms
Evening primrose oil softgel (8–10% GLA)
Dose by GLA content.
Stacks containing Evening Primrose Oil
Public community stacks that include this ingredient.
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