Evening Primrose Oil
GLA-rich oil with evidence for PMS, breast pain, & menopausal symptoms.
Evidence last reviewed: 04 Apr 2026
Evening Primrose Oil is a GLA-rich supplement that may help with PMS, breast pain, and menopausal symptoms. However, the evidence is mixed, and it may not work for everyone.
May lower seizure threshold — avoid with epilepsy medications or phenothiazines
Mild blood-thinning activity — caution with anticoagulants
Summarized study outcomes with population, design, grade, and effect data.
The evidence for Evening Primrose Oil shows moderate benefits for cyclical breast pain and some reduction in menopausal symptoms, but results for PMS mood improvement are inconsistent. The quality of studies varies, indicating a need for more robust research.
PMS / cyclical mastalgia / menopausal symptomsWomen with PMS; perimenopausal women · RCTs (mixed quality)Moderate
Consistent benefit for cyclical breast pain; mixed results for PMS mood; some menopausal hot flush reduction.
Stacks containing Evening Primrose Oil
Public community stacks that include this ingredient.
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Hormonal Balance for Women
Combining Shatavari with Evening Primrose Oil can support hormonal balance in women. Shatavari is an adaptogen that supports reproductive health, while Evening Primrose Oil provides essential fatty acids for hormonal balance.