StackTerminal.Health

BETA

Sodium Butyrate

Sodium butyrate is a short-chain fatty acid supplement that supports gut health by reinforcing gut barrier integrity and modulating immune function. It shows promise in managing conditions like inflammatory bowel disease and irritable bowel syndrome.

gut-healthimmuneanti-inflammatoryanti-cancer
Evidence last reviewed: 20 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Cardiovascular
Blood Pressure
Metabolic
BMI
Gut
Gut Microbiome
Immune
Immune Function
Evidence
5 records
Blood pressure
Patients with hypertensionRCT
PUBMEDLow

Oral butyrate supplementation showed potential in reducing blood pressure in hypertensive patients.

Dose: 600 mg
Abdominal pain frequency
Patients with irritable bowel syndromeRCT
PUBMEDModerate

Microencapsulated sodium butyrate reduced the frequency of abdominal pain in IBS patients.

Dose: 600 mgForm: Microencapsulated
Remission induction
Patients with mild-to-moderate ulcerative colitisRCT
PUBMEDModerate

Microencapsulated sodium butyrate as add-on therapy was effective in inducing remission in ulcerative colitis patients.

Dose: 600 mgForm: Microencapsulated
BMI reduction
Children with obesityRCT
PUBMEDModerate

Butyrate supplementation resulted in a significant reduction in BMI in children with obesity.

Dose: 600 mgDuration: 6 months
Gut microbiota composition
Patients with inflammatory bowel diseaseRCT
PUBMEDModerate

Sodium butyrate altered the gut microbiota by increasing bacteria able to produce SCFA, improving quality of life in ulcerative colitis patients.

Dose: 600 mgDuration: 2 monthsForm: Microencapsulated
Forms
Microencapsulated
Improves stability and delivery to the colon.
Sodium Butyrate Capsules
Common oral form for supplementation.

Stacks containing Sodium Butyrate

Public community stacks that include this ingredient.

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gut-healthanti-inflammatoryimmune

Combining Butyrate with Turmeric can support gut health and reduce inflammation. Butyrate is a short-chain fatty acid that supports gut barrier function, while Turmeric is known for its anti-inflammatory properties.

Sodium Butyrate
600mg
Curcumin Extract
500mg
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