Vitamin B12

Essential cobalamin; deficiency common in vegans, older adults, & those on metformin. Supplementation corrects deficiency reliably.

dailyenergybrainvegans

Evidence last reviewed: 04 Apr 2026

Buy ← Back

Who should avoid this

•those allergic to cobalamin
•individuals with certain rare metabolic disorders

Your fit analysis

Generic — sign in for a personalised view

Generic

In your favour

On the other hand

Evidence

1 record

1 recordBest grade:High

Research shows that B12 supplementation effectively corrects deficiencies and improves energy and neurological symptoms in at-risk populations. While evidence is strong for its benefits, individual responses may vary, and monitoring levels is advisable.

B12 status / neurological function

Deficient adults; vegans; older adults · RCTs + observational

High

Reliably corrects deficiency; improves energy & neurological symptoms in deficient individuals.

Dose: 1 mgDuration: 8–12 weeks

Citation: EFSA guidelines; multiple deficiency correction RCTs

No established benefit in non-deficient adults; high oral doses (1000 mcg) compensate for poor absorption.

Stacks containing Vitamin B12

Explore all →

No public stacks include this supplement yet.

Community Insights

Forms & usage▾

How to take it

Take 250-1000 mcg daily, preferably in sublingual or liquid form for better absorption.

Methylcobalamin

Active form; preferred by some.

Cyanocobalamin

Most studied; highly stable.

Hydroxocobalamin

Long-acting injection form.

Safety & trade-offs1

▾

Note

Cyanocobalamin releases trace cyanide on metabolism — methylcobalamin preferred for those with MTHFR variants or very high-dose supplementation

●High ●Moderate ● Low / note

My notes▾