THC (Tetrahydrocannabinol)
THC is the primary psychoactive component of cannabis, used for pain relief, appetite stimulation, & reducing nausea, particularly in chemotherapy patients.
Evidence last reviewed: 05 Apr 2026
Not a routine supplement — not recommended for self-directed use.
Information here is educational only, not a recommendation to use. See our Safety page.
Evidence is from research or clinical settings — does not imply safety outside supervised contexts.
Moderate evidence supports THC's effectiveness for nausea relief, chronic pain, appetite stimulation, and reducing nightmares in PTSD. However, high-concentration THC products may be linked to mental health issues, necessitating caution in use.
Pain reliefAdults with chronic pain · Systematic reviewModerate
Moderate evidence supports the use of THC for chronic pain relief.
Appetite stimulationAdults with appetite loss · Systematic reviewModerate
THC shows moderate evidence for increasing appetite.
Nausea reliefChemotherapy patients · Systematic reviewModerate
THC is effective as an anti-emetic in chemotherapy-induced nausea.
Mental health outcomesGeneral population · Systematic reviewModerate
High-concentration THC products are associated with mental health issues.
Nightmare reductionPTSD patients · Systematic reviewModerate
THC may reduce the frequency & intensity of nightmares in PTSD.