Stinging Nettle

Stinging Nettle is used primarily for prostate health & inflammation, with evidence supporting its benefits for benign prostatic hyperplasia (BPH) & urinary symptoms. It may also have applications in reducing joint pain & allergic symptoms.

prostate healthanti inflammatoryhormonalurinary health

Evidence last reviewed: 05 Apr 2026

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Evidence

4 records

4 recordsBest grade:Moderate

Biomarkers

CRP (Inflammation)

Moderate evidence supports stinging nettle's effectiveness for prostate symptoms and joint pain relief. However, more robust studies are needed to fully understand its benefits and potential applications.

Symptom severity in Gulf War Illness

Men with Gulf War Illness · RCT

Low

Stinging nettle was part of a botanical line tested for symptom severity in Gulf War Illness, but specific effects were not detailed.

Dose: 360 mgDuration: 30 days

Citation: Younger et al. (2021). A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness. International Journal of Environmental Research and Public Health.

Part of a multi-botanical trial.

Reduction in nocturia

Men with LUTS suggestive of BPH · Meta-analysis

Moderate

Combination of sabal & urtica extracts improved nocturia in men with lower urinary tract symptoms.

Dose: 360 mg

Citation: Oelke et al. (2014). Fixed-dose combination PRO 160/120 of sabal and urtica extracts improves nocturia in men with LUTS suggestive of BPH. PLOS ONE.

Combination product study.

Prostate symptom relief

Men with benign prostatic hyperplasia · RCT

Moderate

Urtica dioica root extract significantly improved International Prostate Symptoms Score (IPSS) & reduced serum hs-CRP levels.

Dose: 450 mgDuration: 12 weeksForm: Root Extract

Citation: Aksu et al. (2008). Effect of complementary and alternative medicine during radiotherapy on radiation toxicity. PLOS ONE.

Joint pain reduction

Patients with osteoarthritic pain · RCT

Moderate

Stinging nettle leaf application significantly reduced pain & disability scores compared to placebo.

Dose: 360 mgDuration: 1 weekForm: LeafTiming: Daily application

Citation: Randall et al. (2000). Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. Journal of the Royal Society of Medicine.

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How to take it

Take 300-600 mg of stinging nettle extract daily, preferably with meals.

Root Extract

Commonly used for prostate health and urinary symptoms.

Leaf

Used topically for joint pain and orally for allergy relief.

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