Sodium Hyaluronate
Sodium Hyaluronate is a form of hyaluronic acid that is used primarily for its joint lubrication and skin hydration properties. It works by retaining moisture and providing cushioning in the joints and skin, leading to improved joint function and skin elasticity.
Evidence last reviewed: 29 Apr 2026
The evidence shows strong benefits for skin hydration and moderate improvements in joint health. However, the anti-aging effects are less convincing and based on observational studies.
Joint HealthAdults with osteoarthritis · Randomized Controlled TrialModerate
Improved joint function and reduced pain.
Skin HydrationAdults with dry skin · Clinical TrialHigh
Increased skin hydration and elasticity.
Anti-Aging EffectsMiddle-aged adults · Observational StudyLow
Reduction in fine lines and wrinkles.
Inflammation ReductionAdults with inflammatory conditions · Meta-AnalysisModerate
Moderate reduction in inflammatory markers.
Strength, Recovery & Longevity Support Stack
This tailored supplement stack is optimized for enhancing strength, recovery, and joint health during your active recovery week. The combination of magnesium, ashwagandha, sodium hyaluronate, vitamin B-complex, and tart cherry supports muscle relaxation, reduces inflammation, and promotes overall longevity, ensuring you bounce back stronger from your high training load.
Longevity Mix (Bryan Johnson)
Bryan Johnson's Blueprint Longevity Mix is the core daily powder from his self-quantified anti-aging protocol. It combines NAD+ pathway support (CaAKG), collagen precursors (Glycine, Lysine, Vitamin C), joint protection (Glucosamine, Sodium Hyaluronate), mitochondrial support (Creatine, CoQ10-adjacent), and antioxidant defence (Glutathione, Taurine). Every ingredient is dosed at clinically relevant levels validated through continuous biomarker tracking.
Forms & usage▾
Take 100-200 mg daily, preferably with water. Timing is flexible, but consistency is key.
Safety & trade-offs2▾
Cost
Context: Higher doses may increase the cost of supplementation.
Absorption
Context: Oral forms may have variable absorption rates.
●High ●Moderate ● Low / note